Results 61 to 70 of about 1,716,279 (361)
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
The American Journal of Bioethics, 2016 Taken as such, default rules do not intrude on autonomy, even if they influence people without persuading them. When default rules give people certain rights automatically (such as the right to vote), they promote autonomy for just that reason. And to the extent that default rules give people the freedom to focus on their most pressing concerns, they ...
openaire +4 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Humanities and Social Sciences Communications, 2020 AbstractCurrent research on autonomous vehicles tends to focus on making them safer through policies to manage innovation, and integration into existing urban and mobility systems. This article takes social, cultural and philosophical approaches instead, critically appraising how human subjectivity, and human-machine relations, are shifting and ...
openaire +5 more sources
How Autonomy Can Legitimate Beneficial Coercion [PDF]
, 2017 Respect for autonomy and beneficence are frequently regarded as the two essential principles of medical ethics, and the potential for these two principles to come into conflict is often emphasised as a fundamental problem.
White, Lucie
core
FEBS Letters, EarlyView.The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Informed Consent Without Autonomy [PDF]
, 2002 This Essay explains why and how the Roman Catholic basis for informed consent is different from the secular basis. It argues that the Catholic basis, which is rooted in natural law, is the better model for society to adopt.
Sulmasy, Daniel P.
core +1 more source
, 2017 Autonomous surgery involves having surgical tasks performed by a robot operating under its own will, with partial or no human involvement. There are several important advantages of automation in surgery, which include increasing precision of care due to ...
Das, Nikhil, Yip, Michael
core +1 more source
The Case for an Autonomy-Centred View of Physician-Assisted Death [PDF]
, 2020 Most people who defend physician-assisted death (PAD) endorse the Joint View, which holds that two conditions—autonomy and welfare—must be satisfied for PAD to be justified. In this paper, we defend an Autonomy Only view.
Davis, Jeremy, Mathison, Eric
core
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source