Results 71 to 80 of about 2,115,919 (388)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

The autonomous life: a pure social view [PDF]

open access: yes, 2013
In this paper I propose and develop a social account of global autonomy. On this view, a person is autonomous simply to the extent to which it is difficult for others to subject her to their wills.
Garnett, Michael
core   +1 more source

Enhanced Solar Photovoltaic System Management and Integration: The Digital Twin Concept

open access: yesSolar
The rapid acceptance of solar photovoltaic (PV) energy across various countries has created a pressing need for more coordinated approaches to the sustainable monitoring and maintenance of these widely distributed installations. To address this challenge,
Olufemi Olayiwola   +3 more
doaj   +1 more source

MODERN STUDENTS’ MENTAL REPRESENTATIONS OF SUCCESS

open access: yesInternational Journal of Cognitive Research in Science, Engineering and Education, 2019
The research is aimed at studying the success mental representations of students who are considered as the modern society members seeking for intellectual and personal resources integration.
Kibal’chenko Irina A.   +1 more
doaj   +1 more source

Insight Under Scrutiny in the Court of Protection: A Case Law Survey

open access: yesFrontiers in Psychiatry, 2020
The concept of patient insight, of a patient’s self-awareness of illness or impairment (and related issues), plays a significant role in clinical discourse and clinical practice.
Sándor Gurbai   +5 more
doaj   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

open access: yesFEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik   +3 more
wiley   +1 more source

Mixed Initiative Systems for Human-Swarm Interaction: Opportunities and Challenges

open access: yes, 2018
Human-swarm interaction (HSI) involves a number of human factors impacting human behaviour throughout the interaction. As the technologies used within HSI advance, it is more tempting to increase the level of swarm autonomy within the interaction to ...
Abbass, Hussein, Hussein, Aya
core   +1 more source

Functional parameters of spermatozoa obtained by a new selection device

open access: yesFEBS Open Bio, EarlyView.
This study compares density gradient centrifugation and the LensHooke CA0™ device for sperm separation. DGC requires multiple steps, specialized equipment, and technical expertise. In contrast, the CA0 device offers key practical and methodological advantages, resulting in a faster, simpler, and more affordable sperm selection method.
Julio C. Chávez   +8 more
wiley   +1 more source

Expanding Autonomy Psychological Need States From Two (Satisfaction, Frustration) to Three (Dissatisfaction): A Classroom-Based Intervention Study

open access: yesJournal of Educational Psychology, 2019
We propose that students experience “autonomy dissatisfaction” when the learning environment is indifferent to their psychological need for autonomy. We hypothesized that (a) students could distinguish this newly proposed need state from both autonomy ...
S. Cheon   +6 more
semanticscholar   +1 more source

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