Results 11 to 20 of about 100,048 (180)

Autoradiography reveals regional metabolic differences in the endometrium of pregnant and nonpregnant mice

Brazilian Journal of Medical and Biological Research, 1998
The rodent endometrium undergoes remarkable modifications during pregnancy, resulting from a redifferentiation of its fibroblasts. During this modification (decidualization), the fibroblasts transform into large, polyhedral cells that establish ...
S.F. Oliveira, P. Abrahamsohn, T.M.T. Zorn   +2 more
doaj   +1 more source

Mechanistic Insights into the Stimulant Properties of Novel Psychoactive Substances (NPS) and Their Discrimination by the Dopamine Transporter—In Silico and In Vitro Exploration of Dissociative Diarylethylamines

Brain Sciences, 2018
Novel psychoactive substances (NPS) may have unsuspected addiction potential through possessing stimulant properties. Stimulants normally act at the dopamine transporter (DAT) and thus increase dopamine (DA) availability in the brain, including nucleus ...
Michelle A. Sahai, Colin Davidson, Neelakshi Dutta, Jolanta Opacka-Juffry   +3 more
doaj   +1 more source

Receptor localization of steroid hormones and drugs: discoveries through the use of thaw-mount and dry-mount autoradiography

Brazilian Journal of Medical and Biological Research, 1998
The history of receptor autoradiography, its development and applications, testify to the utility of this histochemical technique for localizing radiolabeled hormones and drugs at cellular and subcellular sites of action in intact tissues.
W.E. Stumpf
doaj   +1 more source

Modification of dopamine neurotransmission in the nucleus accumbens of rats deficient in n–3 polyunsaturated fatty acids

Journal of Lipid Research, 2000
We studied the effects of a diet chronically deficient in α-linolenic acid, the precursor of long-chain n–3 polyunsaturated fatty acids, on dopaminergic neurotransmission in the shell region of the nucleus accumbens of rats.
Luc Zimmer, Sylvie Delion-Vancassel, Georges Durand, Denis Guilloteau, Sylvie Bodard, Jean-Claude Besnard, Sylvie Chalon   +6 more
doaj   +1 more source

Uranium Traps in Phreatic Sandstone-type Prospect, Taunsa Area, Dera Ghazi Khan, Eastern Sulaiman Range, Pakistan: Evidences from Autoradiography and Optical Microscopy

International Journal of Economic and Environment Geology, 2020
Taunsa uranium occurrence like other uranium resources in Pakistan is hosted by the Late Miocene-Pliocene age Litra Formation of the Siwalik Group molasse sediments.
Rahman Ullah, Nie Fengjuin, Zhang Xin, Zhang Chengyong, Asim Ali, Zhang Pengfei
doaj   +1 more source

Differential Sphingosine-1-Phosphate Receptor-1 Protein Expression in the Dorsolateral Prefrontal Cortex Between Schizophrenia Type 1 and Type 2

Frontiers in Psychiatry, 2022
Understanding the etiology and treatment approaches in schizophrenia is challenged in part by the heterogeneity of this disorder. One encouraging progress is the growing evidence that there are subtypes of schizophrenia.
Ganesh B. Chand, Hao Jiang, J. Philip Miller, C. Harker Rhodes, Zhude Tu, Dean Foster Wong, Dean Foster Wong   +6 more
doaj   +1 more source

Actinide bioimaging in tissues: Comparison of emulsion and solid track autoradiography techniques with the iQID camera. [PDF]

PLoS ONE, 2017
This work presents a comparison of three autoradiography techniques for imaging biological samples contaminated with actinides: emulsion-based, plastic-based autoradiography and a quantitative digital technique, the iQID camera, based on the numerical ...
Stephanie Lamart, Brian W Miller, Anne Van der Meeren, Anissa Tazrart, Jaime F Angulo, Nina M Griffiths   +5 more
doaj   +1 more source

An Enzymatic Platform for Late‐Stage (Radio)isotope Labelling of Oligonucleotides With Methyltransferases

Angewandte Chemie, EarlyView.
State‐of‐the‐art synthesis of radiolabelled oligonucleotides involves multi‐step synthesis with high costs, extended timelines and significant radioactive waste generation. Herein, a dual‐methyltransferase platform enables late‐stage, site‐specific labelling, overcoming these limitations through reduced costs, faster turnaround and minimal radioactive ...
Christopher R. B. Swanson, Ulrich Kauhl, Martin R. Edelmann, Florian P. Seebeck   +3 more
wiley   +2 more sources

Synthesis and Evaluation of Compound Targeting α7 and β2 Subunits in Nicotinic Acetylcholinergic Receptor

Molecules, 2023
Nicotinic acetylcholine receptors (nAChRs) are involved in various central nervous system functions and have also been implicated in several neurodegenerative disorders.
Karanveer Singh, Allyson Ngo, Oshini V. Keerthisinghe, Krystal K. Patel, Christopher Liang, Jogeshwar Mukherjee   +5 more
doaj   +1 more source

Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ1 Receptors in the Brain

Pharmaceuticals, 2014
Sharpless asymmetric dihydroxylation of styrene derivative 6 afforded chiral triols (R)-7 and (S)-7, which were cyclized with tosyl chloride in the presence of Bu2SnO to provide 2-benzopyrans (R)-4 and (S)-4 with high regioselectivity.
Katharina Holl, Dirk Schepmann, Steffen Fischer, Friedrich-Alexander Ludwig, Achim Hiller, Cornelius K. Donat, Winnie Deuther-Conrad, Peter Brust, Bernhard Wünsch   +8 more
doaj   +1 more source