Results 51 to 60 of about 110,609 (237)

Interactive impacts of social deprivation and intranasal oxytocin administration on oxytocin receptor density in prairie vole brains

Frontiers in Behavioral Neuroscience
IntroductionEarly-life social experiences have a profound impact on the development of the brain and behavior. Previous work has shown that prairie voles (Microtus ochrogaster) raised in a socially limited environment (raised by a single mother and ...
Susanna Zheng, George S. Prounis, Alexander G. Ophir   +2 more
doaj   +1 more source

Repeated Clozapine Increases the Level of Serotonin 5-HT1AR Heterodimerization with 5-HT2A or Dopamine D2 Receptors in the Mouse Cortex

Frontiers in Molecular Neuroscience, 2018
G-protein–coupled receptor (GPCR) heterodimers are new targets for the treatment of schizophrenia. Dopamine D2 receptors and serotonin 5-HT1A and 5-HT2A receptors play an important role in neurotransmission and have been implicated in many human ...
Marta Szlachta, Maciej Kuśmider, Paulina Pabian, Joanna Solich, Magdalena Kolasa, Dariusz Żurawek, Marta Dziedzicka-Wasylewska, Agata Faron-Górecka   +7 more
doaj   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Some Metallurgical Applications of Autoradiography [PDF]

, 1961
Macro- and high-resolution methods for autoradiography were used to investigate a number of problems concerning the distribution of uranium and other active elements in metal specimens.
Steunenberg, R. K., Adams, M. D.
core   +1 more source

11C-Autoradiographs to Image Phloem Loading

Frontiers in Forests and Global Change, 2019
Generally, tree species load photoassimilates passively into the phloem, while herbaceous species load actively. These phloem loading strategies have implications for phloem sugar concentration and growth potential.
Michiel Hubeau, Jens Mincke, Jens Mincke, Christian Vanhove, Anaïs Pasiphaé Gorel, Adeline Fayolle, Jackie Epila, Olivier Leroux, Stefaan Vandenberghe, Kathy Steppe   +9 more
doaj   +1 more source

Autoradiography as a safeguards technique [PDF]

, 1978
Autoradiography gives a simultaneous piece count and attribute check for special nuclear material without, however, a quantitative measurement of fissile material. Applications to fuel elements containing plutonium for fast critical assemblies or uranium
Brumbach, S. B.
core  

Electronic autoradiography of Ba-133 particle emissions; diffusion profiles in granitic rocks [PDF]

, 2019
The spatial distribution of barium activity in granitic rocks was measured with two autoradiography techniques; digital autoradiography using phosphor imaging plate technique (Fuji 5100) and filmless electronic autoradiography (i.e.
Muuri, Eveliina, Helariutta, Kerttuli, Koskinen, Lasse, Billon, Sophie, Sorokina, Tatiana, Donnard, Jerome, Martin, Andrew, Siitari-Kauppi, Marja   +7 more
core   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Mitochondrial DNA synthesis studied autoradiographically in various cell types in vivo

Brazilian Journal of Medical and Biological Research, 1998
It is generally accepted that mitochondria are able to proliferate even in postmitotic cells due to their natural turnover and also to satisfy increased cell energy requirements.
H. Korr, C. Kurz, T.O. Seidler, D. Sommer, C. Schmitz   +4 more
doaj   +1 more source