Results 51 to 60 of about 100,048 (180)

Oxytocin Receptor Binding Sites in the Periphery of the Neonatal Prairie Vole

Frontiers in Neuroscience, 2019
The oxytocin receptor (OXTR) has been observed in the periphery of neonatal C57BL/6J mice (Mus musculus), including facial regions and the anogenital area.
Maria A. Greenwood, Maria A. Greenwood, Elizabeth A. D. Hammock, Elizabeth A. D. Hammock   +3 more
doaj   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

Synthesis and Preliminary Evaluation of a 2-Oxoquinoline Carboxylic Acid Derivative for PET Imaging the Cannabinoid Type 2 Receptor

Pharmaceuticals, 2014
Cannabinoid receptor subtype 2 (CB2) has been shown to be up-regulated in activated microglia and therefore plays an important role in neuroinflammatory and neurodegenerative diseases such as multiple sclerosis, amyotrophic lateral sclerosis and ...
Linjing Mu, Roger Slavik, Adrienne Müller, Kasim Popaj, Stjepko Čermak, Markus Weber, Roger Schibli, Stefanie D. Krämer, Simon M. Ametamey   +8 more
doaj   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, Volume 46, Issue 5, Page 1362-1389, September 2026.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

CB1 and LPA1 Receptors Relationship in the Mouse Central Nervous System

Frontiers in Molecular Neuroscience, 2019
Neurolipids are a class of bioactive lipids that are produced locally through specific biosynthetic pathways in response to extracellular stimuli. Neurolipids are important endogenous regulators of neural cell proliferation, differentiation, oxidative ...
Estíbaliz González de San Román, Iván Manuel, Catherine Ledent, Jerold Chun, Fernando Rodríguez de Fonseca, Fernando Rodríguez de Fonseca, Guillermo Estivill-Torrús, Guillermo Estivill-Torrús, Luis Javier Santín, Luis Javier Santín, Rafael Rodríguez Puertas, Rafael Rodríguez Puertas   +11 more
doaj   +1 more source

Increased Binding of [18F]Nifene, a PET Imaging Probe for α4β2* Nicotinic Acetylcholinergic Receptors in Hippocampus–Subiculum of Postmortem Human Parkinson's Disease Brain

Synapse, Volume 80, Issue 5, September 2026.
[18F]Nifene, a PET imaging probe for α4β2* nicotinic acetylcholine receptors, was used to discretely measure changes in hippocampus (HP) and subiculum (SUB) of postmortem Parkinson's disease (PD) cases compared to cognitively normal (CN) cases. Significant increased [18F]nifene binding in PD was observed.
Jogeshwar Mukherjee, Fariha Karim, Allyson Ngo, Christopher Liang, Geidy E. Serrano, Thomas G. Beach   +5 more
wiley   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, Volume 16, Issue 8, Page 1593-1601, August 2026.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Characterization and calibration of the iQID digital autoradiography system for direct quantitative imaging of beta‐emitters in tissue samples

Medical Physics, Volume 53, Issue 8, August 2026.
Abstract Background Autoradiography provides microscale mapping of radionuclide distributions, offering a promising approach to complement nuclear medicine imaging for small‐scale radiopharmaceutical therapy (RPT) research. However, while quantitative protocols for α‐emitters are well‐established, comparable methods for β‐emitters, such as the widely ...
Ohyun Kwon, Sean P. Jollota, Adedamola O. Adeniyi, Justin J. Jeffery, Joseph B. Schulz, Lauren E. Wehner, Malick Bio Idrissou, Eduardo Aluicio‐Sarduy, Brian W. Miller, Denis E. Bergeron, Reinier Hernandez, Larry A. DeWerd, Bryan P. Bednarz   +12 more
wiley   +1 more source

In Situ Bacterioplankton Growth Partitioning by High‐Resolution Metatranscriptomics

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
Bacterial growth and primary production are key ecological indicators, yet often measured in bulk. Using metatranscriptomics, the authors identify FtsZ expression to track dividing cells (A, B). Phylogenetic placement of transcripts (C–E) enables linking growth activity to specific taxa (E, F), potentially bridging bulk measurements with fine‐scale ...
J. Cesar Ignacio‐Espinoza, Yuxuan Zou, Andrew Long, Shengwei Hou, David M. Needham, Jed A. Fuhrman   +5 more
wiley   +1 more source

The Development and Application of Tritium-Labeled Compounds in Biomedical Research

Molecules
With low background radiation, tritiate compounds exclusively emit intense beta particles without structural changes. This makes them a useful tool in the drug discovery arsenal.
Yu Teng, Hong Yang, Yulin Tian
doaj   +1 more source