Results 61 to 70 of about 110,609 (237)

Epilepsy surgery: From bench to the clinics

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Double label autoradiography--an improvement.

open access: yes, 1986
A convenient method for double-label autoradiography is described that uses an aqueous mountant, Gelutol (polyvinyl alcohol), which keeps the gelatin spacer in the final autoradiograph permanently swollen to a thickness of around 18 microns in contrast ...
D Wynford-Thomas   +2 more
core   +2 more sources

Ultrastructural, autoradiographic and electrophoretic examinations of Chara tomentosa spermiogenesis

open access: yesActa Societatis Botanicorum Poloniae, 2014
Ultrastructure of a spermatid nucleus changes many times during spermiogenesis. Condensed chromatin forms irregular clusters during phases I-II, a continuous ring adjacent to a nuclear envelope during phases III-V and a network occupying the whole ...
Maria Kwiatkowska   +2 more
doaj   +1 more source

c‐Met‐Targeted Imaging Agents: Progress and Challenges

open access: yesiRADIOLOGY, EarlyView.
This review summarizes recent advances in c‐Met‐targeted imaging probes, including hepatocyte growth factor (HGF) ligands, antibodies, peptides, and small molecules across magnetic resonance imaging (MRI), positron emission tomography (PET), single‐photon emission computed tomography (SPECT), and optical imaging modalities.
Yonghao Li   +4 more
wiley   +1 more source

Freeze-fracture autoradiography. Progress towards a routine technique.

open access: yes, 1979
Freeze-fracture autoradiography was introduced in 1976 as a new technique for the autoradiography of diffusible compounds at the electron microscope level. With the original approach coating of the frozen replicated specimens was performed in a cryostat
E Rix, A Schiller, R Taugner
core   +1 more source

METTL14 Regulates Myocardial Infarction Progression via m6A‐Dependent Modulation of OTUD1‐Mediated Deubiquitination of DUSP6

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial infarction (MI) is the most severe clinical manifestation of coronary artery diseases (CVD) and serves as a critical driver of sudden cardiac death and heart failure (HF). Its pathophysiology begins with the abrupt cessation of coronary blood flow, leading to severe ischemia and subsequent cardiomyocyte necrosis. This study aimed to
Cheng‐Cheng Wei   +2 more
wiley   +1 more source

Indirect Striatal Projection Neurons Drive a D2 Receptor‐Dependent Pathway to Dyskinesia and Dystonia

open access: yesMovement Disorders, EarlyView.
D2 receptor ablation in indirect‐pathway striatal neurons reduces or abolishes dyskinetic and dystonic behaviors induced by L‐DOPA or D2 receptor agonists, respectively. Contralateral turning is reduced, while forward locomotion is increased. These effects are associated with modulation of neuronal activity in dorsal striatum and external globus ...
Laura Andreoli   +5 more
wiley   +1 more source

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg   +2 more
wiley   +1 more source

Hemipteran vectors of stylet‐borne plant viruses: Aphids lead the charge

open access: yesInsect Science, EarlyView.
Among all sap‐feeding hemipterans, aphids stand out by far as the most important vectors of noncirculative plant viruses. Compared to whiteflies and mealybugs, aphids’ highly specialized stylet anatomy and distinct feeding behaviors contribute, together with other features of their biology, to their remarkable efficiency in transmitting stylet‐borne ...
Yu Fu, Stefano Colella, Marilyne Uzest
wiley   +1 more source

Summary of autoradiography protocol.

open access: yes, 2014
Autoradiography experiments utilized PCMB, PD123319, or losartan, to unmask non-AT1, non-AT2 binding, or block AT2 and AT1 receptors, respectively. Non-radioiodinated Ang II was utilized to define specific binding of 125I-SI Ang II to Ang II binding ...
Catalina Bretón (5660335)   +9 more
core   +1 more source

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