Results 71 to 80 of about 110,609 (237)

Image processing methods in digital autoradiography.

open access: yes, 2018
Autoradiography is a common method in biomedical research for detecting and measuring biodistributions of labelled biomolecules within a specimen. The conventional method is based on using film or film-emulsions for the image acquisition.
Kokkinou, Eleni.
core   +1 more source

Covalent fluorescent probes for 2‐arachidonoylglycerol metabolic pathways

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent fluorescent probes have emerged as versatile chemical tools to visualise active enzymes in complex biological systems. When tailored for specific applications, ranging from activity‐based protein profiling for drug development to high spatiotemporal resolution imaging of enzymatic activities, these probes provide unique insights into ...
Nick D. F. Puijmbroeck   +1 more
wiley   +1 more source

Autoradiography imaging for confirmatory purpose.

open access: yes, 2014
Ex vivo autoradiography from a mouse injected with 18F-FDG. The ligated left carotid artery (LC) showed high amount of 18F-FDG uptake compared to the non-ligated right carotid artery (RC).
Lei Xing (129950)   +5 more
core   +1 more source

Autoradiography with the electron microscope: properties of photographic emulsions [PDF]

open access: yes, 1968
In this chapter, some current techniques of autoradiography with the electron microscope will be discussed, as well as some properties of the three photographic emulsions most commonly used for this purpose, namely, Gevaert NUC 307, Ilford LA, and Kodak ...
Rajewsky, Manfred F., Hülser, Dieter F.
core   +1 more source

Wee1 kinase differentially regulates maize CDKA2;1a and CDKB1;1

open access: yesThe FEBS Journal, EarlyView.
In eukaryotes, Wee1 kinase inhibits the kinase activity of CDK/Cyc complexes through phosphorylation of a conserved residue in the CDK moiety. Wee1 is also present in plants, but has been scarcely studied. We have studied maize Wee1 regulation of CDKA/CycD2;2a or CDKB/CycD2;2a complexes.
Mingyar N. López‐Hernández   +4 more
wiley   +1 more source

Ligand binding represses bacterial histidine kinase activity by inhibiting its dimerization

open access: yesThe FEBS Journal, EarlyView.
PdtaS is a kinase in the pathogen Mycobacterium tuberculosis that senses copper and nitric oxide and controls virulence gene expression, but how the kinase senses these compounds was unclear. We show that PdtaS is active as a dimer with each monomer phosphorylating the other in trans.
Gaurav D. Sankhe   +6 more
wiley   +1 more source

The use of autoradiography in the indentification of selected bacteria in the European corn borer

open access: yes, 1971
Scientists trying to find biological controls for insect pests are hamperedd by the absence of rapid methods for screening organisms such as bacteria for potential pathogenicity. An organism must grow in the gut of the insect to be pathogenic.
Warn, Beverly J., 1946-
core  

Calibration of 14C-plastic standards for quantitative autoradiography with 33P.

open access: yes, 1994
Probes labeled with 33P have potential for widespread use in in situ hybridization because they are better able to detect relatively scarce mRNAs compared with probes labeled with 35S, but the relatively short half-life of 33P is a disadvantage when it ...
J F Breininger   +3 more
core   +1 more source

The pharmacology of gepants in migraine: A scoping review on mechanisms, clinical applications, and combination strategies

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone   +5 more
wiley   +1 more source

The MacBrain Resource Center (MBRC) rhesus macaque embryonic brain histology datasets

open access: yesJournal of Anatomy, EarlyView.
We introduce the MacBrain Resource Center (MBRC) Collections of rhesus macaque embryonic brain tissue. Here, we illustrate histo‐ and immunohistology from our dynamically growing Collection 6, which currently contains >10,000 zoomable and downloadable images from n = 14 male and female embryos from early to late in gestation.
Valeria Mendoza‐Silva   +11 more
wiley   +1 more source

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