Results 91 to 100 of about 30,053 (265)

Surgical cyst decortication in autosomal dominant polycystic kidney disease [PDF]

, 2013
PURPOSE: To provide a summary of the relevant literature regarding the impact of surgical cyst decortication on hypertension, renal function, and pain management in patients with autosomal dominant polycystic kidney disease (ADPKD).
Bhayani, Sam B, Clayman, Ralph V, Figenshau, R. Sherburne, Haseebuddin, Mohammed, Millar, Melissa, Tanagho, Youssef S   +5 more
core   +2 more sources

Pleiotropic Effects of the NSAID Fenamates on Chloride Channels: Opportunity for Ion Channelopathies?

Pharmacology Research &Perspectives, Volume 13, Issue 4, August 2025.
ABSTRACT Chloride channels are involved in many cellular processes, including cell volume regulation, modulation of cell excitability, and electrolyte and water secretion. Mutations of these proteins are associated with heterogeneous diseases such as myotonia, cystic fibrosis, epilepsy, deafness, lysosomal storage disease, and various kinds of renal ...
Paola Laghetti, Ilaria Saltarella, Simone Dell'Atti, Jean‐François Desaphy, Concetta Altamura   +4 more
wiley   +1 more source

Autosomal dominant polycystic kidney disease and coronary artery dissection or aneurysm: A systematic review [PDF]

, 2016
Importance Autosomal dominant polycystic kidney disease (ADPKD) has been associated with cardiovascular abnormalities such as intracranial and aortic aneurysms.
Lopes, JA, Neves, JB, Rodrigues, FB
core   +1 more source

Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease [PDF]

New England Journal of Medicine, 2012
The course of autosomal dominant polycystic kidney disease (ADPKD) is often associated with pain, hypertension, and kidney failure. Preclinical studies indicated that vasopressin V(2)-receptor antagonists inhibit cyst growth and slow the decline of kidney function.In this phase 3, multicenter, double-blind, placebo-controlled, 3-year trial, we randomly
Torres VE, Chapman AB, Devuyst O, Gansevoort RT, Grantham JJ, Higashihara E, Perrone RD, Krasa HB, Ouyang J, Czerwiec FS, Tempo team, Gross P, Schulze B, Bichet D, Chauveau D, Peeters P, Voiculescu M, Manunta P, Tuazon J, Watnick T, Goral S, Horie S, Nutahara K, Torres V, Chapman A, Devuyst O, Gansevoort R, Higashihara E, Perrone R, Ouyang J, Czerwiec F, Goldstein S, Cowley B, Fukagawa M, Torra R, Wei LJ, Cook T, Toto R, Agarwal R, August P, Bakris G, Beddhu S, Corwin H, Ruilope L, Rosa-Diez G, De La Fuente J, Martin R, Massari P, Novoa P, Rial M, Wasserman A, Faull R, Fraser I, Johnson D, Pedagagos E, Lian M, Pollock C, Cooper B, Rangan G, Russ G, McDonald S, Thomas M, Khoo D, Walker R, Devuyst O, Pirson Y, Peeters P, Laecke V, Van der Niepen P, Sennesael J, Barre P, Alam A, Bichet D, Soroka S, Dieperink H, Strandgaard S, Petersen L, Berthoux F, Berthoux F, Canaud B, Gontiers-Picard A, Chauveau D, Huart A, Combe C, Delmas Y, Dussol B, Berthoux F, Laville M, Guebre-Egziabher F, Mignon F, Michel C, Rieu P, Noel N, Ryckelynck J, Lobbedez T, Dellanna F, Kleophas W, Gross P, Feldkamp T, Witzke O, Nurnberger J, Schulze B, Zeltner R, Walz G, Zeier M, Sommerer C, Bianchi S, Capasso G, Miranda N, Magistroni R, Manunta P, Bracale M, Remuzzi G, Rota S, Villa G, Tilocca P, Asahi K, Kato T, Endo M, Umezono T, Fujigaki Y, Kato A, Fukatsu A, Hasegawa H, Tayama Y, Hasegawa M, Horie S, Hosoya T, Hanaoka K, Iehara N, Fukatsu A, Iino Y, Tsuruoka S, Imai E, Isaka Y, Imai E, Ishimura E, Ito S, Sato H, Kamata K, Sakamoto H, Kamura K, Kato T, Kusano E, Muto S, Kuwahara M, Matsubara A, Yorioka N, Mochizuki T, Muto S, Horie S, Narita I, Naya Y, Nihei N, Yukio N, Nishio S, Nitta K, Tsuchiya K, Nutahara K, Okamura M, Sasaki S, Rai T, Seta K, Sugawara A, Shibazaki S, Sugawara A, Sugiyama S, Tabei K, Takaichi K, Tomita K, Kitamura K, Tsukamoto Y, Tsuruya K, Nakano T, Ubara Y, Watanabe T, Yamamoto T, Yorioka N, Yoshida K, Ishii D, Yuzawa Y, Hasegawa M, Gansevoort R, Meijer E, Vervloet M, Ciechanowski K, Wisniewska M, Gutowska-Jablonska M, Marcinkowska-Królewicz M, Klatko W, Wiśniewski T, Klinger M, Krajewska M, Ksiazek A, Orłowska G, Malecki R, Gontarek-Kacprzak J, Nowicki M, Makówka A, Rutkowski B, Volovat C, Maxwell A, Mottl A   +202 more
openaire   +10 more sources

Effects of combined treatment with zibotentan and dapagliflozin compared to dapagliflozin alone in patients with diabetic and non‐diabetic chronic kidney disease

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4311-4319, August 2025.
Abstract Aims To evaluate whether type 2 diabetes status modifies the efficacy and safety of combining zibotentan (zibo), a selective endothelin receptor antagonist, and dapagliflozin (dapa) compared to placebo plus dapagliflozin in individuals with chronic kidney disease (CKD).
Victor Wasehuus, J. David Smeijer, Phil Ambery, Peter J. Greasley, Emma Wijkmark, David C. Wheeler, Peter Rossing, Hiddo J. L. Heerspink   +7 more
wiley   +1 more source

Renal Transplantation in Autosomal Dominant Polycystic Kidney Disease [PDF]

European Medical Journal Nephrology, 2015
Autosomal dominant polycystic kidney disease (ADPKD) affects approximately 1 in 1,000 people in the general population. The natural history of ADPKD includes the progression of chronic kidney disease to end-stage renal disease (ESRD) in a large ...
Andrzej Kulesza, Longin Niemczyk, Mariusz Niemczyk   +2 more
doaj  

Translation, cultural adaptation and aplication of a pain questionnaire for patients with polycystic kidney disease [PDF]

, 2010
INTRODUCTION: Pain is a common symptom in patients with autosomal dominant polycystic kidney disease (ADPKD), affecting around 60% of cases. OBJECTIVE: Translate a pain questionnaire developed and validated for ADPKD in USA into Portuguese and to perform
Eloi, Samara Rodrigues Moreira, Heilberg, Ita Pfeferman, Nishiura, José Luiz   +2 more
core   +2 more sources

The Pathogenesis of Autosomal Dominant Polycystic Kidney Disease [PDF]

Nephron Experimental Nephrology, 2006
In individuals with autosomal dominant polycystic kidney disease (ADPKD), renal function deteriorates as the kidneys become replaced by multitudes of fluid-filled cysts. Although the PKD genes were identified a decade ago, the pathway(s) leading from mutation to disease remain the subject of intense investigation.
openaire   +3 more sources

Diffusion Tensor Imaging (DTI) as a Non‐Invasive Tool for Assessing Pediatric Kidney Transplants: A Feasibility Study

Pediatric Transplantation, Volume 29, Issue 5, August 2025.
Our study demonstrates the feasibility of using diffusion tensor imaging (DTI) to evaluate pediatric kidney transplants. Significant differences in fractional anisotropy (FA) and track length were observed between transplanted and healthy kidneys, reflecting altered microstructural organization.
Suraj D. Serai, Tatiana Morales, Daniel Vossough, Sandra Amaral, Hansel J. Otero, Bernarda Viteri Baquerizo   +5 more
wiley   +1 more source

Caffeine intake by patients with autosomal dominant polycystic kidney disease [PDF]

, 2012
Because caffeine may induce cyst and kidney enlargement in autosomal dominant polycystic kidney disease (ADPKD), we evaluated caffeine intake and renal volume using renal ultrasound in ADPKD patients.
Baxmann, Alessandra Calábria, Heilberg, Ita Pfeferman, Nishiura, José Luiz, Vendramini, Larissa Collis   +3 more
core   +2 more sources