Results 71 to 80 of about 4,548,243 (309)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

An Efficient Analytical Approach to Investigate the Dynamics of a Misaligned Multirotor System

open access: yesMathematics, 2020
This paper deals with the analytical investigation of a multirotor system connected by a flexible coupling subjected to dynamic angular misalignment. A novel analytical approach is employed for this purpose, namely the optimal auxiliary functions method,
Nicolae Herisanu, Vasile Marinca
doaj   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

open access: yes
Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra   +9 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Space-Vector Analysis of the Twelve-Pulse Diode Bridge Rectifier Operation for the Auxiliary Circuit Current Determination Providing the Optimal Line Currents’ THD

open access: yesEnergies
Three-phase diode bridge rectifiers are widely employed in various industrial applications because of their inherent simplicity, robustness, low electromagnetic interference and good overall performance.
Jaroslaw Rolek, Grzegorz Utrata
doaj   +1 more source

Numerical modelling of series-parallel cooling systems in power plant

open access: yesE3S Web of Conferences, 2017
The paper presents a mathematical model allowing one to study series-parallel hydraulic systems like, e.g., the cooling system of a power boiler's auxiliary devices or a closed cooling system including condensers and cooling towers.
Regucki Paweł   +2 more
doaj   +1 more source

Time-dependent framework for energy and charge currents in nanoscale systems

open access: yes, 2018
The calculation of time-dependent charge and energy currents in nanoscale systems is a challenging task. Nevertheless it is crucial for gaining a deep understanding of the relevant processes at the nanoscale.
Croy, Alexander   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Cost Effective, High Efficiency Integrated Systems Approach to Auxilliary Electric Motors [PDF]

open access: yes, 2003
The CARAT program, carried out by Kinetic Art & Technology Corporation (KAT), has been one of the most commercially successful KAT R&D programs to date. Based on previous development of its technology, KAT designed, constructed and tested a highly efficient motor and controller system under this CARAT program with supplemental commercial funding ...
Jr., Roy Kessinger   +5 more
openaire   +4 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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