Results 141 to 150 of about 2,118 (260)

Reflex seizures and epilepsy surgery: A network approach case‐based exploration

open access: yesEpileptic Disorders, EarlyView.
Abstract Context Reflex seizures (RS) are defined by their consistent provocation by specific stimuli, encompassing a broad range from elementary sensory inputs to complex cognitive tasks. While RS are often encountered in clinical practice, their surgical management remains sparsely reported and poorly systematized.
Olivier Aron   +6 more
wiley   +1 more source

Localizing value of verbal automatisms, vocal automatisms, singing, and humming: A systematic review

open access: yesEpileptic Disorders, EarlyView.
Abstract Objective We performed a systematic review of the localizing and lateralizing value of verbal automatisms, vocal automatisms, ictal singing, and humming in focal epilepsy with the view to summarize the state‐of‐the‐art clinico‐anatomical correlations in the field and help guide interpretation of ictal semiology within the framework of ...
Vit Vsiansky, Martin Pail, Milan Brazdil
wiley   +1 more source

Epilepsy‐associated SCN2A‐L1342P mutation drives network hyperexcitability and widespread transcriptomic changes in human cortical organoids

open access: yesEpilepsia, EarlyView.
Abstract Objective SCN2A pathogenic mutations, such as the recurrent heterozygous Nav1.2‐L1342P, are monogenic causes of epilepsy. In this human‐induced pluripotent stem cell–derived model system, we aim to investigate the molecular and cellular mechanisms underlying SCN2A‐L1342P‐associated pathology. Methods Using a human male induced pluripotent stem
Maria I. Olivero‐Acosta   +26 more
wiley   +1 more source

Perils and progress in epilepsy surgery utilization: Twenty‐five years later

open access: yesEpilepsia, EarlyView.
Abstract More than 25 years have passed since the first randomized controlled trial (RCT) established that surgery is superior to continued anti‐seizure medication (ASM) for drug‐resistant temporal lobe epilepsy, and nearly as long since a joint practice parameter urged that appropriate surgical candidates be referred to a specialized center for ...
Dario J. Englot
wiley   +1 more source

Validating objective and scalable speech markers of depression across two independent psychiatric cohorts. [PDF]

open access: yesAnn Gen Psychiatry
Menne F   +8 more
europepmc   +1 more source

Cross‐material memory prediction: Influence of preoperative visual memory on postoperative verbal memory change after left anterior temporal lobe resection in people with epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Left anterior temporal lobe resection (TLR) in people with epilepsy is associated with a high risk of postoperative verbal memory decline. Whereas substantial evidence supports the role of preoperative verbal memory in predicting postoperative verbal memory change, the potential contribution of preoperative visual memory has been ...
Lea Marie Reisch   +6 more
wiley   +1 more source

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