Results 41 to 50 of about 442 (142)

Furtherin vitroevaluation of cytotoxicity of the marine natural product derivative 4′-leucine-avarone

open access: yesNatural Product Research, 2014
The cytotoxicity of 4′-leucine-avarone, amino derivative of the sponge Dysidea avara secondary metabolite avarone, was evaluated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay in vitro against seven human solid tumours for the first time.
Pejin B   +5 more
openaire   +4 more sources

Argentine plant extracts active against polymerase and ribonuclease H activities of HIV-1 reverse transcriptase [PDF]

open access: yes, 1999
Lipophilic and hydrophilic extracts of four Argentine plants (Gamochaeta simplicaulis Cabr. 1, Achyrocline flaccida Wein. D. C. 2, Eupatorium buniifolium H. et A. 3, and Phyllanthus sellowianus Muell. Arg.
Broussalis, A. (Adriana)   +13 more
core  

SKRINING SENYAWA ANTIBAKTERI EKSTRAK SPONS DARI PERAIRAN KUPANG, NUSA TENGGARA TIMUR [PDF]

open access: yes, 2016
Bakteri Escherichia coli dan Staphylococcus aureus merupakan bakteri yang resisten terhadap antibiotik atau disebut Multi Drugs Resistance (MDR). Bakteri tersebut menimbulkan berbagai penyakit pada manusia dan hewan.
Karna Radjasa, Ocky   +2 more
core  

Electrochemical reactivity of biologically active quinone/hydroquinone sesquiterpenoids on glassy carbon electrodes [PDF]

open access: yes, 1987
The redox reactivity of avarone and avarol, a quinone/hydroquinone couple isolated from the marine sponge Dysidea avara, was investigated by cyclic voltammetry, using a glassy carbon electrode. Both oxidation of avarol and reduction of avarone in aqueous
Davidović, A.   +6 more
core   +2 more sources

Supplementary material for the article: Jeremić, M.; Pešić, M.; Dinić, J.; Banković, J.; Novakovićc, I.; Šegan, D.; Sladić, D. Simple Avarone Mimetics as Selective Agents against Multidrug Resistant Cancer Cells. European Journal of Medicinal Chemistry 2016, 118, 107–120. https://doi.org/10.1016/j.ejmech.2016.04.011 [PDF]

open access: yes, 2016
Supplementary material for: [https://doi.org/10.1016/j.ejmech.2016.04.011]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789 ...
Banković, Jasna   +6 more
core   +2 more sources

Antiviral lead compounds from marine sponges [PDF]

open access: yes, 2010
Marine sponges are currently one of the richest sources of pharmacologically active compounds found in the marine environment. These bioactive molecules are often secondary metabolites, whose main function is to enable and/or modulate cellular ...
Kaur, Mandeep   +2 more
core   +1 more source

The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells

open access: yesNatural Product Research, 2017
This study aimed to screen in vitro antitumour activity of the redox couple avarol/avarone against the human malignant glioma cell line U-251 MG for the first time. Compared both with avarol and positive controls used (temozolomide and doxorubicin), avarone was found to be the most active compound with IC50 value below 1 μM (IC50 0.68 ± 0.04 μM, 96 h).
Pejin Boris   +4 more
openaire   +3 more sources

Interakcije antitumorskog seskviterpenskog hidrohinona avarola sa DNA in vitro [PDF]

open access: yes, 2007
Changes in electrophoresis pattern after interaction of supercoiled plasmid pBR322 DNA with avarol was studied at a micromolar concentration of reactants under mild reaction conditions.
Gasic, Miroslav J.   +4 more
core   +2 more sources

Evaluation of genotoxic potential of avarol, avarone, and its methoxy and methylamino derivatives in prokaryotic and eukaryotic test models

open access: yesDrug and Chemical Toxicology, 2018
In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3′-methoxyavarone, 4′-(methylamino)avarone and 3′-(methylamino)avarone was evaluated and compared to cytostatics commonly used in chemotherapy (5-fluorouracil, etoposid, and cisplatin).
Kolarević, Stoimir   +9 more
openaire   +6 more sources

Home - About - Disclaimer - Privacy