Marine invertebrate metabolites with anticancer activities: solutions to the "supply problem" [PDF]
, 2016 Marine invertebrates provide a rich source of metabolites with anticancer activities and several marine-derived agents have been approved for the treatment of cancer.
Chandra, S. +4 more
core +3 more sources
New perspective on type 2 diabetes and obesity treatment: study and development of new natural/synthetic inhibitors of tyrosine phosphatase 1B (PTP1B). [PDF]
, 2023 Type 2 diabetes mellitus (T2DM) is a complex disease characterized by impaired glucose homeostasis and serious long-term complications. First line therapeutic options for T2DM treatment are monodrug therapies, often replaced by multidrugs therapies to ...
Genovese, Massimo
core
Chemical modification of b-lactoglobulin by quinones [PDF]
Journal of the Serbian Chemical Society, 2003 The avarone/avarol quinone/hydroquinone couple, as well as their derivatives show considerable antitumor activity. In this work, covalent modifications of b-lactoglobulin, isolated from cow milk, by avarone, its model compound 2-tert-butyl-1,4 ...
DUSAN SLADIC +5 more
doaj
Further in vitro biological activity evaluation of amino-, thio- and ester-derivatives of avarol [PDF]
, 2015 The acetylcholinesterase inhibitory and/or antitumour activities of amino-, thio-and ester-derivatives of avarol selected were evaluated for the first time at in vitro conditions. Avarol-3',4'-dithioglycol (1) and avarol-4'-(3) mercaptopropionic acid (3)
De Rosa, Salvatore +4 more
core +1 more source
Protein covalent modification by biologically active quinones [PDF]
Journal of the Serbian Chemical Society, 2004 The avarone/avarol quinone/hydroquinone couple shows considerable antitumor activity. In this work, covalent modification of b-lactoglobulin by avarone and its derivatives as well as by the synthetic steroidal quinone 2,5(10)-estradiene-1,4,17-trione and
MIROSLAV J. GASIC +7 more
doaj
Regioselektivnost konjugovane adicijena monoalkil-1,4-benzohinone [PDF]
, 2002 The regioselectivity of the reaction of conjugate addition of thiols, amines, methanol and hydrogen chloride with the monoalkyl-1,4-benzoquinones avarone and 2-tert-butyl-1,4-benzoquinone was investigated.
Božić, Tatjana T. +5 more
core +2 more sources
A New Bioactive Sesquiterpenoid Quinone from the Mediterranean Sea Marine Sponge
Natural Product Communications, 2013 Investigation of the marine sponge Dysidea avara , family Dysideidae, afforded a new sesquiterpene (-)- N -methylmelemeleone-A ( 5 ), in addition to four known sesquiterpenes (+)-avarol ( 1 ), (+)-avarone ( 2 ), (-)-3′-methylaminoavarone ( 3 ) and (-)-4′-
Ashraf Nageeb El-Sayed Hamed +7 more
doaj +1 more source
Bioprospecting: a CAM Frontier
, 2005 Evidence-Based Complementary and Alternative Medicine, Volume 2, Issue 1, Page 1-3, 2005.
Edwin L. Cooper
wiley +1 more source
CAM, eCAM, Bioprospecting: The 21st Century Pyramid
, 2005 Evidence-Based Complementary and Alternative Medicine, Volume 2, Issue 2, Page 125-127, 2005.
Edwin L. Cooper
wiley +1 more source
Influence of Merosesquiterpenoids from Marine Sponges on Seedling Root Growth of Agricultural Plants
Natural Product Communications, 2016 The impact of the merosesquiterpenoids avarol ( 1 ), avarone ( 2 ), 18-methylaminoavarone ( 3 ), melemeleone A ( 4 ), isospongiaquinone ( 5 ), ilimaquinone ( 6 ), and smenoquinone ( 7 ), isolated from marine sponges of the Dictyoceratida order, was ...
Elena L. Chaikina +2 more
doaj +1 more source