Results 21 to 30 of about 194 (112)

Chemical modification of b-lactoglobulin by quinones [PDF]

Journal of the Serbian Chemical Society, 2003
The avarone/avarol quinone/hydroquinone couple, as well as their derivatives show considerable antitumor activity. In this work, covalent modifications of b-lactoglobulin, isolated from cow milk, by avarone, its model compound 2-tert-butyl-1,4 ...
DUSAN SLADIC, NENAD MILOSAVIC, NATASA BOZIC, TATJANA BOZIC, ZORAN VUJCIC, IRENA NOVAKOVIC   +5 more
doaj  

Protein covalent modification by biologically active quinones [PDF]

Journal of the Serbian Chemical Society, 2004
The avarone/avarol quinone/hydroquinone couple shows considerable antitumor activity. In this work, covalent modification of b-lactoglobulin by avarone and its derivatives as well as by the synthetic steroidal quinone 2,5(10)-estradiene-1,4,17-trione and
MIROSLAV J. GASIC, BOGDAN SOLAJA, DRAGANA MILIC, TATJANA BOZIC, NATASA BOZIC, ZORAN VUJCIC, IRENA NOVAKOVIC, DUSAN SLADIC   +7 more
doaj  

A New Bioactive Sesquiterpenoid Quinone from the Mediterranean Sea Marine Sponge

Natural Product Communications, 2013
Investigation of the marine sponge Dysidea avara , family Dysideidae, afforded a new sesquiterpene (-)- N -methylmelemeleone-A ( 5 ), in addition to four known sesquiterpenes (+)-avarol ( 1 ), (+)-avarone ( 2 ), (-)-3′-methylaminoavarone ( 3 ) and (-)-4′-
Ashraf Nageeb El-Sayed Hamed, Wim Wätjen, Roland Schmitz, Yvonni Chovolou, RuAngelie Edrada-Ebel, Diaa T. A. Youssef, Mohammed Salah Kamel, Peter Proksch   +7 more
doaj   +1 more source

Bioprospecting: a CAM Frontier

, 2005
Evidence-Based Complementary and Alternative Medicine, Volume 2, Issue 1, Page 1-3, 2005.
Edwin L. Cooper
wiley   +1 more source

CAM, eCAM, Bioprospecting: The 21st Century Pyramid

, 2005
Evidence-Based Complementary and Alternative Medicine, Volume 2, Issue 2, Page 125-127, 2005.
Edwin L. Cooper
wiley   +1 more source

Influence of Merosesquiterpenoids from Marine Sponges on Seedling Root Growth of Agricultural Plants

Natural Product Communications, 2016
The impact of the merosesquiterpenoids avarol ( 1 ), avarone ( 2 ), 18-methylaminoavarone ( 3 ), melemeleone A ( 4 ), isospongiaquinone ( 5 ), ilimaquinone ( 6 ), and smenoquinone ( 7 ), isolated from marine sponges of the Dictyoceratida order, was ...
Elena L. Chaikina, Natalia K. Utkina, Mikhail M. Anisimov   +2 more
doaj   +1 more source

Commentary on Traditional and Modern Biomedical Prospecting: Part II—The Benefits by Werner E. G. Müller, Heinz C. Schröder, Matthias Wiens, Sanja Perović‐Ottstadt, Renato Batel and Isabel M. Müller: Anti‐Protozoa and Antiviral Activities of Non‐Cytotoxic Truncated and Variant Analogues of Mussel Defensin by P. Roch, A. Beschin and E. Bernard

, 2004
Evidence-Based Complementary and Alternative Medicine, Volume 1, Issue 2, Page 207-209, 2004.
Edwin L. Cooper
wiley   +1 more source

Furtherin vitroevaluation of cytotoxicity of the marine natural product derivative 4′-leucine-avarone

Natural Product Research, 2014
The cytotoxicity of 4′-leucine-avarone, amino derivative of the sponge Dysidea avara secondary metabolite avarone, was evaluated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay in vitro against seven human solid tumours for the first time.
Pejin B, Iodice C, Tommonaro G, Bogdanovic G, Kojic V, De Rosa S   +5 more
openaire   +4 more sources

The redox couple avarol/avarone in the fight with malignant gliomas: the case study of U-251 MG cells

Natural Product Research, 2017
This study aimed to screen in vitro antitumour activity of the redox couple avarol/avarone against the human malignant glioma cell line U-251 MG for the first time. Compared both with avarol and positive controls used (temozolomide and doxorubicin), avarone was found to be the most active compound with IC50 value below 1 μM (IC50 0.68 ± 0.04 μM, 96 h).
Pejin Boris, Tommonaro Giuseppina, Glumac Miodrag, Jakimov Dimitar, Kojic Vesna   +4 more
openaire   +3 more sources

The Avarol-Avarone Redox Behaviour in Acetonitrile

Croatica Chemica Acta, 1986
The oxidation of avarol and the reduction of avarone were studied at a Pt electrode in acetonitrile-tetraethyl-ammonium perchlorate media. The oxidation of avarol in acetonitrile takes place by formation of a two electron oxidation product, presumably the »protonated avarone«. The reduction of avarone takes place in two steps by formation of the stable
Gašić, Miroslav J., Sladić, Dušan, Tabaković, Ibro, Davidović, Asima   +3 more
openaire   +2 more sources