Interakcije antitumorskog seskviterpenskog hidrohinona avarola sa DNA in vitro [PDF]
Changes in electrophoresis pattern after interaction of supercoiled plasmid pBR322 DNA with avarol was studied at a micromolar concentration of reactants under mild reaction conditions.
Gasic, Miroslav J. +4 more
core +2 more sources
In this study, mutagenic and genotoxic potential of anti-tumor compounds avarol, avarone, and its derivatives 3′-methoxyavarone, 4′-(methylamino)avarone and 3′-(methylamino)avarone was evaluated and compared to cytostatics commonly used in chemotherapy (5-fluorouracil, etoposid, and cisplatin).
Kolarević, Stoimir +9 more
openaire +6 more sources
The Algal Meroterpene 11-Hydroxy-11-O-Methylamentadione Ameloriates Dextran Sulfate Sodium-Induced Colitis in Mice [PDF]
Inflammatory bowel disease (IBD) is a complex class of immune disorders. Unfortunately, a treatment for total remission has not yet been found, while the use of natural product-based therapies has emerged as a promising intervention.
Antonio Alcaide +11 more
core +2 more sources
Approaches to the Total Synthesis of Puupehenone-Type Marine Natural Products [PDF]
Puupehenones have been isolated from the marine sponge Chondrosia chucalla, which belong to a growing family of natural products with more than 100 members.
Cheng, Yun-Fei +2 more
core +1 more source
Natural products and their mimics have a high probability of engaging with biological targets. Hence, natural products have historically been a valuable source of medicines.
core
Búsqueda de cabezas de serie con actividad frente a Leishmania [PDF]
El presente estudio se basa en la síntesis, purificación y evaluación biológica de modelos sintéticos basados en las formas oxidadas de sesquiterpenos marinos identificados en el alga roja Laurencia johnstonii.
Marrero Ramos, Tamara
core
Pharmacological Activities of Extracts and Compounds Isolated from Mediterranean Sponge Sources. [PDF]
Di Cesare Mannelli L +11 more
europepmc +1 more source
Modular total syntheses of trans-clerodanes and sesquiterpene (hydro)quinones via tail-to-head cyclization and reductive coupling strategies. [PDF]
Zhu W, Yin Q, Lou Z, Yang M.
europepmc +1 more source
Supplementary data for article : Kolarević, S.; Milovanović, D.; Kračun-Kolarević, M.; Kostić, J.; Sunjog, K.; Martinović, R.; Đorđević, J.; Novaković, I.; Sladić, D.; Vuković-Gačić, B. Evaluation of Genotoxic Potential of Avarol, Avarone, and Its Methoxy and Methylamino Derivatives in Prokaryotic and Eukaryotic Test Models. Drug and Chemical Toxicology 2019, 42 (2), 130–139. https://doi.org/10.1080/01480545.2017.1413108 [PDF]
Supplementary material for: [https://doi.org/10.1080/01480545.2017.1413108]Related to published version: [http://cherry.chem.bg.ac.rs/handle/123456789 ...
Kolarević, Stoimir +9 more
core
Promising Antiparasitic Natural and Synthetic Products from Marine Invertebrates and Microorganisms. [PDF]
Zhang M, Zhang Q, Zhang Q, Cui X, Zhu L.
europepmc +1 more source

