Results 121 to 130 of about 576,687 (323)

Clinical and Echocardiographic Insights Into Right Heart Masses: A Retrospective Study in China (2010–2023)

open access: yesCancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background This study aimed to analyze the clinical and echocardiographic characteristics, pathological profiles, and outcomes of right heart masses, and to explore the role of echocardiography in the evaluation of these masses. Methods We retrospectively analyzed 171 patients with echocardiographically diagnosed and pathologically confirmed ...
Lei Liu   +7 more
wiley   +1 more source

Inter-Rater Reliability & Value of the Hawkins Sign

open access: yesFoot & Ankle Orthopaedics
Category: Trauma; Ankle Introduction/Purpose: Hawkins III talus neck fractures are associated with elevated rates of complications, notably avascular necrosis, which range between 40% to 70%.
Logan Lake   +8 more
doaj   +1 more source

Core Decompression Augmented With Autologous Bone Marrow Aspiration Concentrate for Early Avascular Necrosis of the Femoral Head

open access: yesArthroscopy Techniques, 2016
Lack of necessary perfusion to the femoral head can lead to necrosis of the underlying bone (avascular necrosis) and result in femoral and acetabular surface changes in advanced stages.
Lucas Arbeloa-Gutierrez, M.D.   +3 more
doaj   +1 more source

MeMAGEN: A Phase IIa/IIb open‐label trial of memantine testing safety and tolerability in sickle cell patients

open access: yesHemaSphere, Volume 10, Issue 1, January 2026.
ABSTRACT Administration of memantine, an antagonist of the N‐methyl‐ d‐aspartate receptor, prevents Ca2+ overload and dehydration of red blood cells (RBCs) in patients with sickle cell disease (SCD). The objectives of the 1‐year dose‐escalation Phase IIa/IIb Memantine trial (MeMAGEN – NCT 03247218) with 17 SCD patients who were under stable ...
Ariel Koren   +7 more
wiley   +1 more source

Natural‐History Mapping of Lysosomal Storage Disorders (LSDs): Gaucher Disease as a Model for Precision Care

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.
ABSTRACT Natural‐history datasets have become pivotal for drug development and for shaping clinical‐practice guidelines in rare diseases, yet many lysosomal storage disorders would benefit from deep phenotyping and modern analytic methods. Our objective was to integrate the past decade of genomic, cellular, treatment‐outcome, and regulatory advances ...
Noor Ul Ain   +2 more
wiley   +1 more source

Treatment Outcomes of Undisplaced Femoral Neck Fractures Treated with Cannula Screws in Patients Over 65 Years of Age

open access: yesمجله دانشکده پزشکی اصفهان, 2019
Background: Femoral neck fracture is a common discomfort in elderly people, often caused by osteoporosis and a trauma with low energy, such as falling. Considering that during the time, it seems that the effect of treatment with prosthesis is better than
Hossein Akbari-Aghdam   +1 more
doaj   +1 more source

In Vitro Evaluation of Hemiarthroplasty Bearing Materials: A Scoping Review (Part I)

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 1, January 2026.
ABSTRACT Hemiarthroplasty is used to treat joint damage confined to one side, aiming to preserve the remaining healthy cartilage and bone while addressing conditions like femur fractures and osteonecrosis; however, challenges persist due to cartilage wear and inconsistent clinical outcomes.
Victoria P. Marino   +6 more
wiley   +1 more source

THE DILEMMA OF AVASCULAR NECROSIS [PDF]

open access: yesBasrah Journal of Surgery, 2004
Mohammed Hassan Kubba
doaj   +1 more source

Necrosis avascular de cabeza femoral en pacientes con enfermedad de Gaucher tipo I : tratamiento mediante artroplastia total de cadera no cementada [PDF]

open access: yes, 2017
El 80% de los pacientes con enfermedad de Gaucher presentan manifestaciones óseas, siendo la necrosis avascular de la cabeza femoral una de las que mayor limitación produce y la primera causa de intervención quirúrgica osteoarticular.
Blas Dobón, J.A.   +4 more
core  

In Vivo Evaluation of Hemiarthroplasty Bearing Materials Using Animal Models: A Scoping Review (Part II)

open access: yesJournal of Orthopaedic Research, Volume 44, Issue 1, January 2026.
ABSTRACT Hemiarthroplasty is commonly used to treat damage localized to one side of a synovial joint, maximally preserving the patient's opposing healthy bone and cartilage; however, challenges remain due to accelerated wear of the cartilage articulating with the implant surface. This scoping review summarized investigations of hemiarthroplasty bearing
Landon M. Begin   +5 more
wiley   +1 more source

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