Results 71 to 80 of about 1,115 (163)

DataSheet2_Avatrombopag for the treatment of thrombocytopenia induced by chemotherapy in patients with solid tumors: A multicenter, open-label, single-arm trial.docx

, 2022
Objective: To explore the effect and safety of avatrombopag for chemotherapy-induced thrombocytopenia (CIT).Methods: This multicenter, open-label, single-arm trial enrolled CIT patients in eight centers from October 2020 to April 2021.
Liting Qian (9278642), Chunbao Zang (11102184), Yufei Zhao (775411), Jin Huang (146235), Changlu Hu (13866692), Bihong Zhan (13866698), Xiaofeng Zhu (36670), Kaiyang Ding (3840079), Yayun Cui (12567190), Yifu He (5881085), Congyin Tu (13866695)   +10 more
core   +1 more source

Thromboelastography‐Guided Laparoscopic Splenectomy in a Patient With Immune Thrombocytopenia and Recent Drug‐Eluting Stent Placement: A Case Report

Case Reports in Anesthesiology, Volume 2026, Issue 1, 2026.
Background Perioperative management of patients with immune thrombocytopenia (ITP) is particularly challenging when complicated by recent coronary stenting requiring dual antiplatelet therapy (DAPT), due to competing risks of bleeding and thrombosis. Case Presentation We report the case of an 80‐year‐old male with refractory ITP and recent drug‐eluting
Josue Gaona, Janki Patel, Benjamin Tan
wiley   +1 more source

Platelet volume could predict the efficacy of thrombopoietin receptor agonists in the treatment of patients with primary immune thrombocytopenia

Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.
Decreased platelet production and increased peripheral platelet destruction were two pathological processes in ITP. High MPV could reflect hyper‐productive thrombopoiesis under TPO‐RA treatment. NLR is a marker of immune profile in ITP, it could reflect platelet destruction of platelet.
Bei Xu, Lili Ji, Hao Pang, Luya Cheng, Yanxia Zhan, Pu Chen, Hao Chen, Jie Cheng, Yunfeng Cheng   +8 more
wiley   +1 more source

Efficacy and safety and analysis of thrombopoietin receptor agonists for the treatment of immune thrombocytopenia in adults: analysis of a systematic review and network meta-analysis of randomized controlled trials and results of real-world safety data

Frontiers in Medicine
This study aimed to compare the efficacy and safety of thrombopoietin receptor agonists (TPO-RA) in the treatment of immune thrombocytopenia (ITP) in adults.
Yumeng Liu, Ni Zhang, Tingting Jiang, Yanping Li, Yu Xiong, Yao Liu   +5 more
doaj   +1 more source

Case Report: A case of pediatric persistent refractory ITP responsive to avatrombopag [PDF]

Immune thrombocytopenia (ITP) is a rare hematologic disorder characterized by low platelet counts due to an immune-mediated destruction of platelets. While corticosteroids, intravenous immunoglobulin (IVIG) are the mainstays of treatment, a subset of ...
Sau, Antonella, Di Prinzio, Gianfranco, Santoro, Nicole, Russo, Anna Caterina, Onofrillo, Daniela, Di Ianni, Mauro   +5 more
core   +1 more source

Avatrombopag plus fostamatinib combination as treatment in patients with multirefractory immune thrombocytopenia

Immune thrombocytopenia (ITP) refractory to multiple therapies may require a combination of drugs targeting different mechanisms and targets. In this retrospective, multicentre, international study, we report the safety and effectiveness of avatrombopag ...
Bastida, José-María, Piquer-Monsonis, Dolores, Pedrote, Begoña, Abdel-Kader Martín, Laila, Ghanima, Waleed, Ruíz Sainz, Elena, Nuñez-Vázquez, Ramiro, Mingot-Castellano, María Eva, Canaro, Mariana   +8 more
core   +2 more sources

Investigation of the ABCB1 Gene Polymorphism and Food Effects on the Avatrombopag Pharmacokinetics in Chinese Individuals: A Population Pharmacokinetic/Pharmacodynamic Analysis

Pharmaceuticals
Background/Objectives: Avatrombopag (AVA), a thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease, exhibits significant pharmacokinetic (PK) variability, particularly under fasting conditions.
Xin Liu, Lulu Chen, Gehang Ju, Chao Li, Bijue Liu, Yunzhou Fei, Xintong Wang, Yang Gao, Qingfeng He, Xiao Zhu, Dongsheng Ouyang   +10 more
doaj   +1 more source

Plenary Abstracts Session & Oral Presentations

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source