Avenanthramide-C reduces the viability of MDA-MB-231 breast cancer cells through an apoptotic mechanism [PDF]
Cancer Cell International, 2017 Background Avenanthramides (AVN) are a relatively unstudied family of phytochemicals that could be novel chemotherapeutics. These compounds, found in oats, are non-toxic to healthy cells and have been shown to reduce viability of human colon and liver ...
Jordan Hastings, Jason Kenealey
doaj +5 more sources
Avenanthramide C as a novel candidate to alleviate osteoarthritic pathogenesis. [PDF]
BMB Rep, 2021 Osteoarthritis (OA) is a degenerative disorder that can result in the loss of articular cartilage. No effective treatment against OA is currently available. Thus, interest in natural health products to relieve OA symptoms is increasing.
Tran TT +6 more
europepmc +6 more sources
Avenanthramide-C as Alzheimer’s Disease-Modifying Therapy: Early and Sustained Intervention Prevents Disease Progression in Mouse Models [PDF]
CellsMost approved drugs for Alzheimer’s disease (AD) are indicated for early to moderate stages and primarily target amyloid-beta or neurotransmitter systems.
Alen Benhur Pravin Nathan +7 more
doaj +3 more sources
Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats [PDF]
Frontiers in Molecular BiosciencesBackgroundDoxorubicin (DOX) drugs used in cancer treatment can cause various adverse effects, including hepatotoxicity. Natural-derived constituents have shown promising effects in alleviating chemotherapy-induced toxicities.
Maha Abdullah Alwaili +11 more
doaj +4 more sources
Corrigendum: Avenanthramide-C ameliorate doxorubicin-induced hepatotoxicity via modulating Akt/GSK-3β and Wnt-4/β-Catenin pathways in male rats [PDF]
Frontiers in Molecular BiosciencesMaha Abdullah Alwaili +11 more
doaj +3 more sources
Oat Avenanthramide-C (2c) Is Biotransformed by Mice and the Human Microbiota into Bioactive Metabolites [PDF]
The Journal of Nutrition, 2015 Avenanthramides (AVAs), which are found exclusively in oats, may play an important role in anti-inflammation and antiatherogenesis. Although the bioavailability of AVAs has been investigated previously, little is known about their metabolism.The aim of the present study was to investigate the metabolism of avenanthramide-C (2c), one of the major AVAs ...
Pei, Wang +5 more
openaire +4 more sources
Exploring Nutritional Quality and Bioactive Compounds in Oat Mediterranean Landraces and Cultivars [PDF]
AntioxidantsOat (Avena sativa L.) is increasingly recognized as a functional food due to its unique profile of antioxidant and health-promoting compounds. Beyond its traditional role, our study reveals that Mediterranean landraces and related species harbour ...
Elena Prats +5 more
doaj +2 more sources
Avenanthramide-C Shows Potential to Alleviate Gingival Inflammation and Alveolar Bone Loss in Experimental Periodontitis. [PDF]
Mol Cells, 2023 Periodontal disease is a chronic inflammatory disease that leads to the gradual destruction of the supporting structures of the teeth including gums, periodontal ligaments, alveolar bone, and root cementum. Recently, interests in alleviating symptoms of periodontitis (PD) using natural compounds is increasing.
Kim SJ +8 more
europepmc +3 more sources
Synthesis of Avenanthramide C and Its Analogs Utilizing Classical Condensation, Saponification and Acidification [PDF]
ACS OmegaSe Myeong Choi +5 more
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Oat-based milk alternatives: the influence of physical and chemical properties on the sensory profile. [PDF]
Front NutrOat-based milk alternatives (OMAs) have become increasingly popular, perhaps due to their low allergenicity and preferred sensory attributes when compared to other milk alternatives.
McCarron R +4 more
europepmc +3 more sources