Results 131 to 140 of about 4,073,428 (289)

A customer Requirement Identification System for Product Concept Development

open access: yes, 2009
[[abstract]]The electronic commerce is widely and quickly developed in recent years due to the spread of the internet. To take the advantage of electronic commerce, the enterprise is constantly searching for the best way to serve the customers whose ...
Yan-Da Jou
core  

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Average Convexity in Communication Situations [PDF]

open access: yes
In this paper we study inheritance properties of average convexity in communication situations. We show that the underlying graph ensures that the graphrestricted game originating from an average convex game is average convex if and only if every ...
Slikker, M.
core  

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Measuring the policy effects of changes in reserve requirement ratios [PDF]

open access: yes
The monetary base is the sum of high-powered money and an adjustment factor that measures changes in reserve requirement ratios. This adjustment factor is calculated so that it responds to changes in deposit levels in addition to changes in reserve ...
Scott E. Hein, Joseph H. Haslag
core  

Average Rainfall and Water Requirements of Bundelkhand Region: Causes, Consequences, and Solutions

open access: yesInternational Journal for Research in Applied Science and Engineering Technology
Abstract: The Bundelkhand region, receiving an annual rainfall of approximately 1000 mm, with nearly 90% occurring during the short span of July and August, is traversed by major rivers. However, this region grapples with a severe water crisis exacerbated by factors such as burgeoning agriculture, population growth, unpredictable rainfall patterns, the
openaire   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Dealing with Limited Overlap in Estimation of Average Treatment Effects [PDF]

open access: yes
Estimation of average treatment effects under unconfounded or ignorable treatment assignment is often hampered by lack of overlap in the covariate distributions.
Richard K. Crump   +3 more
core  

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