Results 121 to 130 of about 4,704,446 (291)

Non-overlap Average Treatment Effect Bounds

34 pages, 3 ...
Susmann, Herbert P., McClean, Alec, Díaz, Iván   +2 more
openaire   +2 more sources

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Modelling Contract Farming Impact on Poultry Farm Income: Lessons from the Nigerian Anchor-Borrower Outgrowers’ Programme

Journal of Agriculture and Environment for International Development
Contract farming was introduced in Nigeria to address the challenges faced by smallholder farming households in realising farming objectives. Therefore, this study examined the effectiveness of the Anchor-borrower Outgrowers’ Programme in fulfilling one
Olabisi Damilola Omodara, Oluwemimo Oluwasola, Akinsola Temitope Oyebanji   +2 more
doaj   +1 more source

Estimation of Heterogeneous Treatment Effects on Hazard Rates [PDF]

Consider a setting where a treatment that starts at some point during a spell (e.g. in unemployment) may impact on the hazard rate of the spell duration, and where the impact may be heterogeneous across subjects.
Gaure, Simen, Røed, Knut, van den Berg, Gerard J., Zhang, Tao   +3 more
core  

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Deep learning for causal inference using low birth weight in midwife-led continuity care intervention in north Shoa zone, Ethiopia

Frontiers in Artificial Intelligence
IntroductionLow birth weight (LBW), under 2,500 g, poses health risks, though not always requiring treatment. Early detection of high-risk pregnancies enables preventive care, improving outcomes for mother and baby.
Wudneh Ketema Moges, Wudneh Ketema Moges, Wudneh Ketema Moges, Awoke Seyoum Tegegne, Aweke A. Mitku, Aweke A. Mitku, Esubalew Tesfahun, Solomon Hailemeskel   +7 more
doaj   +1 more source

Identification of Treatment Effects Using Control Functions in Models with Continuous, Endogenous Treatment and Heterogeneous Effects [PDF]

We use the control function approach to identify the average treatment effect and the effect of treatment on the treated in models with a continuous endogenous regressor whose impact is heterogeneous.
C. Meghirx, E. Vytlacil, J. J. Heckmanz, J.P. Florensy   +3 more
core  

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

When the Early Bird Catches the Worm: The Impact of Training in Retail [PDF]

We econometrically evaluate the performance effects of a six month e-learning programme in a large retail chain with monthly data on sales revenue, for four years using panel regressions.
Fahr, René, Hinerasky, Christiane
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source