Results 141 to 150 of about 19,276,699 (283)
Estimating and Testing Models with Many Treatment Levels and Limited Instruments [PDF]
Many empirical microeconomic studies estimate econometric models that assume a single finite-valued discrete endogenous regressor (for example: different levels of schooling), exogenous regressors that are additively separable and enter the equation ...
Lance Lochner, Enrico Moretti
core
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
IEEE AccessParkinson’s disease (PD) detection through voice analysis faces two fundamental challenges: traditional machine learning methods lack clinical interpretability due to their correlational nature, while existing causal inference approaches struggle ...
Meghana Sunil +2 more
doaj +1 more source
The effect of providing free autopoweroff plugs to households on electricity consumption - A field experiment [PDF]
Experimental evidence of the effect of providing cheap energy saving technology to households is sparse. We present results from a field experiment in which autopoweroff plugs are provided free of charge to randomly selected households. We use propensity
Troels Fjordbak +3 more
core
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Transportation Research Interdisciplinary PerspectivesThis study estimates the causal effects of traffic crashes on driving behavior and habits, focusing on total annual distance driven (km) and the proportion of kilometers driven above the posted speed limit, in urban areas, and at night.
Catalina Bolancé +3 more
doaj +1 more source
A note on estimation of the average treatment effect and average partial effect in nonlinear models [PDF]
In the literature on program impact evaluation, the popular impact parameters can the average treatment effect, the average treatment effect on the treated, the average partial effect, and the average partial effect on the treated.
Cuong Nguyen Viet
core
Appendix D. Model-average effect sizes between treatment groups.
, 2016 Model-average effect sizes between treatment ...
Margot L. Hessing-Lewis (2911403) +4 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source