Results 151 to 160 of about 20,519,205 (284)

College Education and Wages in the U.K.: Estimating Conditional Average Structural Functions in Nonadditive Models with Binary Endogenous Variables [PDF]

open access: yes
Recent studies debate how the unobserved dependence between the monetary return to college education and selection into college can be characterized. This paper examines this question using British data.
Klein, T.J.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Adaptive Experimental Design Using the Propensity Score [PDF]

open access: yes
Many social experiments are run in multiple waves, or are replications of earlier social experiments. In principle, the sampling design can be modified in later stages or replications to allow for more efficient estimation of causal effects.
Keisuke Hirano   +2 more
core   +2 more sources

Replication data for: "Testing Local Average Treatment Effect Assumptions"

open access: yes
Mourifie, Ismael, and Wan, Yuanyuan, (2017) "Testing Local Average Treatment Effect Assumptions." Review of Economics and Statistics 99:2, 305 ...
Mourifie, Ismael, Wan, Yuanyuan
core   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Self-Attentive Quantile GAN With Causally Grounded Machine Learning for Vocal Biomarker Discovery in Parkinson’s Disease Detection

open access: yesIEEE Access
Parkinson’s disease (PD) detection through voice analysis faces two fundamental challenges: traditional machine learning methods lack clinical interpretability due to their correlational nature, while existing causal inference approaches struggle ...
Meghana Sunil   +2 more
doaj   +1 more source

A note on estimation of the average treatment effect and average partial effect in nonlinear models [PDF]

open access: yes
In the literature on program impact evaluation, the popular impact parameters can the average treatment effect, the average treatment effect on the treated, the average partial effect, and the average partial effect on the treated.
Cuong Nguyen Viet
core  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Estimating the causal impact of crashes on drivers’ behavior through a difference-in-differences quasi-experimental design

open access: yesTransportation Research Interdisciplinary Perspectives
This study estimates the causal effects of traffic crashes on driving behavior and habits, focusing on total annual distance driven (km) and the proportion of kilometers driven above the posted speed limit, in urban areas, and at night.
Catalina Bolancé   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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