The National Treatment Purchase Fund: treating people faster.
The National Treatment Purchase Fund (NTPF) was set up by the Government to treat patients like you, who have been longest on public hospital waiting lists for an operation.
National Treatment Purchase Fund
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
The Causal Effect of Parents' Schooling on Children's Schooling - A Comparison of Estimation Methods [PDF]
We review the empirical literature that estimates the causal effect of parent’s schooling on child’s schooling, and conclude that estimates differ across studies.
Mikael Lindahl +2 more
core
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Comparison of random forest methods for conditional average treatment effect estimation with a continuous treatment. [PDF]
Tabib S, Larocque D.
europepmc +1 more source
An alternative robust estimator of average treatment effect in causal inference. [PDF]
Liu J, Ma Y, Wang L.
europepmc +1 more source
From Classroom to Wedding Aisle: The Effect of a Nationwide Change in the Compulsory Schooling Law on Age at First Marriage in the UK [PDF]
Does more schooling causes a delay in marriage? Using a nationwide change in the compulsory schooling law in the UK as a source of exogenous variation in education, this paper estimates the causal effect of schooling on age at first marriage.
Adireksombat, Kampon +1 more
core
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Pseudo-random Number Generator Influences on Average Treatment Effect Estimates Obtained with Machine Learning. [PDF]
Naimi AI, Yu YH, Bodnar LM.
europepmc +1 more source
Learning about social programs from experiments with random assignment of treatments [PDF]
The importance of social programs to a diverse population creates a legitimate concern that the findings of evaluations be widely credible. The weaker are the assumptions imposed, the more widely credible are the findings.
C. F. Manski
core

