Results 201 to 210 of about 20,519,205 (284)

Partial Identification of the Average Treatment Effect Using Instrumental Variables: Review of Methods for Binary Instruments, Treatments, and Outcomes. [PDF]

J Am Stat Assoc, 2018
Swanson SA, Hernán MA, Miller M, Robins JM, Richardson TS.   +4 more
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Matching plus regression adjustment for the estimation of the average treatment effect on survival outcomes: a case study with mosunetuzumab in relapsed/refractory follicular lymphoma. [PDF]

BMC Med Res Methodol
Di Maio D, Mitchell SA, Batson S, Keeney E, Thom HHZ.   +4 more
europepmc   +1 more source

A doubly robust estimator for the average treatment effect in the context of a mean-reverting measurement error. [PDF]

Biostatistics, 2017
Lenis D, Ebnesajjad CF, Stuart EA.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Directed Acyclic Graph Assisted Method For Estimating Average Treatment Effect. [PDF]

J Biopharm Stat
Sun J, Duncan S, Pal S, Kong M.
europepmc   +1 more source

Approaches to the Estimation of the Local Average Treatment Effect in a Regression Discontinuity Design. [PDF]

Scand Stat Theory Appl, 2016
O'Keeffe AG, Baio G.
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Estimating the average treatment effect on survival based on observational data and using partly conditional modeling. [PDF]

Biometrics, 2017
Gong Q, Schaubel DE.
europepmc   +1 more source

Model-Averaged Propensity Scores for Estimating the Average Treatment Effect under Treatment Effect Heterogeneity

Estimating the Average Treatment Effect using Propensity Score Weighting is highly sensitive to the choice of propensity score model, especially when there is heterogeneity in treatment effects and limited overlap in covariates. In practice, the true treatment assignment mechanism is rarely known, and ATE estimates based on a single propensity score ...
openaire   +1 more source