Results 71 to 80 of about 311,621 (266)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Erratum to: Center Manifold Method in the Asymptotic Integration Problem for Functional Differential Equations with Oscillatory Decreasing Coefficients. II (in Russian)

open access: yesМоделирование и анализ информационных систем, 2016
We correct the computational mistakes in paper: Nesterov P. N. Center Manifold Method in the Asymptotic Integration Problem for Functional Differential Equations with Oscillatory Decreasing Coefficients. II. In: Modeling and Analysis of Information Systems.
P. N. Nesterov
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

EVOLUTION OF THE ROTATIONAL MOTION OF A SATELLITE WITH FLEXIBLE VISCOELASTIC RODS ON THE ELLIPTIC ORBIT

open access: yesРоссийский технологический журнал, 2018
The rotational motion of an artificial satellite in the central Newtonian force field is investigated. The satellite is modeled as a symmetric solid with rigid viscoelastic rods rigidly attached along the symmetry axis and with a spherical inertia tensor.
E. V. Sadovnikova, A. V. Shatina
doaj   +1 more source

Spatial averaging method based on adaptive weight for imaging photoplethysmography. [PDF]

open access: yesJ Biomed Opt, 2023
Ryu J   +5 more
europepmc   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Limit cycles bifurcating from the periodic annulus of cubic homogeneous polynomial centers

open access: yesElectronic Journal of Differential Equations, 2015
We obtain an explicit polynomial whose simple positive real roots provide the limit cycles which bifurcate from the periodic orbits of any cubic homogeneous polynomial center when it is perturbed inside the class of all polynomial differential systems
Jaume Llibre   +2 more
doaj  

Averaging method for problems on quasiclassical asymptotics

open access: yesСовременная математика: Фундаментальные направления
The averaging method is developed for operators with rapidly oscillating coefficients, intended for use in problems of quasiclassical asymptotics and not assuming a periodic structure of coefficient oscillations.
S. Yu. Dobrokhotov, V. E. Nazaikinskii
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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