Results 91 to 100 of about 11,252,851 (310)

Within-project and cross-project defect prediction based on model averaging

open access: yesScientific Reports
Software defect prediction has an important impact on the national economy and financial service industry. Discovering defective modules in the early stage of software development has great significance.
Tong Li, Zhong Wang, Peibei Shi
doaj   +1 more source

Model Averaging for Accelerated Failure Time Models with Missing Censoring Indicators

open access: yesMathematics
Model averaging has become a crucial statistical methodology, especially in situations where numerous models vie to elucidate a phenomenon. Over the past two decades, there has been substantial advancement in the theory of model averaging. However, a gap
Longbiao Liao, Jinghao Liu
doaj   +1 more source

Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP‐ribose) glycohydrolase inhibitor

open access: yesFEBS Open Bio, EarlyView.
We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley   +1 more source

On the Limit Cycles of a Class of Generalized Kukles Polynomial Differential Systems via Averaging Theory

open access: yesInternational Journal of Differential Equations, 2015
We apply the averaging theory of first and second order to a class of generalized Kukles polynomial differential systems to study the maximum number of limit cycles of these systems.
Amar Makhlouf, Amor Menaceur
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Iterrative Correction of Measurement with Averaging of Dithered Samples

open access: yesAdvances in Electrical and Electronic Engineering, 2008
Self-calibration techniques could eliminate measurement errors caused by time changes and component aging. For ADC performance enhancement also averaging is necessary.
Miroslav Kamensky, Karol Kovac
doaj  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

The Selection of Industry 4.0 Technologies Through Aczel-Alsina Information Based on Circular Bipolar Complex Fuzzy Uncertainty: An Operational Perspective

open access: yesIEEE Access
This manuscript aims to find the most key steps and considerations for selecting industry 4.0 technology. For this, we evaluate the technique of circular bipolar complex fuzzy (CBCF) information.
Zeeshan Ali   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy