Results 61 to 70 of about 10,537,968 (352)

Pre-averaging based estimation of quadratic variation in the presence of noise and jumps : theory, implementation, and empirical evidence [PDF]

, 2010
This paper provides theory as well as empirical results for pre-averaging estimators of the daily quadratic variation of asset prices. We derive jump robust inference for pre-averaging estimators, corresponding feasible central limit theorems and an ...
Hautsch, Nikolaus, Podolskij, Mark
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

An approach to Atanassov's interval-valued intuitionistic fuzzy multi-attribute decision making based on prospect theory [PDF]

International Journal of Computational Intelligence Systems, 2015
Prospect theory is a very effective method to express behavioral decision making under uncertainty. This paper attempts to develop a method to multi-attribute decision making with Atanassov's interval-valued intuitionistic fuzzy information using ...
Fanyong Meng, Chunqiao Tan, Xiaohong Chen   +2 more
doaj   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Limit cycles for fourth-order autonomous differential equations

Electronic Journal of Differential Equations, 2012
We provide sufficient conditions for the existence of periodic solutions of the fourth-order differential equation $$ ddddot x -(lambda+mu) dddot x +(1+lambda mu)ddot x -(lambda+mu)dot x+lambda mu x = varepsilon F(x, dot x, ddot x, dddot x ...
Jaume Llibre, Amar Makhlouf
doaj  

New Operators for Aggregating Intuitionistic Fuzzy Information With Their Application in Decision Making

IEEE Access, 2018
Aggregation of intuitionistic fuzzy information is a hot topic in Atanassov's intuitionistic fuzzy set theory, which has attracted much interest from researchers in recent years. In this paper, a series of new aggregation operators and weighted averaging
Cheng-Li Fan, Yafei Song, Qiang Fu, Lei Lei, Xiaodan Wang   +4 more
doaj   +1 more source

Spherically Symmetric Solutions in Macroscopic Gravity

, 2008
Schwarzschild's solution to the Einstein Field Equations was one of the first and most important solutions that lead to the understanding and important experimental tests of Einstein's theory of General Relativity.
A. Borriello, A. Krasiński, A. Paranjape, A.A. Coley, A.A. Coley, A.A. Coley, A.G. Reiss, C.M. Will, G.F.R. Ellis, J. Plebański, J.P. Boersma, J.P. Ostriker, K. Lake, L. Bergström, M. Kasai, M. Persic, M.F. Shirokov, N.V. Zotov, R. J. van den Hoogen, R.A. Isaacson, R.A. Isaacson, R.J. Hoogen van den, R.M. Zalaletdinov, R.M. Zalaletdinov, R.M. Zalaletdinov, S. Bharadwaj, S. Bildhauer, S. Perlmutter, S. Tremaine, S.W. Hawking, T. Buchert, T. Buchert, T. Futamase, T. Futamase, T.W. Noonan, T.W. Noonan, U. Nucamendi, V.C. Rubin, V.C. Rubin, V.C. Rubin, V.C. Rubin, Y. Sofue   +41 more
core   +1 more source

Averaging operations for lattice gauge theories [PDF]

Communications in Mathematical Physics, 1985
Usually renormalization group transformations are defined by some averaging operations. In this paper we study such operations for lattice gauge fields and for gauge transformations. We are interested especially in characterizing some classes of field configurations on which the averaging operations are regular (e.g., analytic).
openaire   +3 more sources