Results 61 to 70 of about 724,647 (339)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Singular Perturbation Theory for PWM AC/DC Converters: Cascade Nonlinear Control Design and Stability Analysis

open access: yesIranian Journal of Electrical and Electronic Engineering, 2022
In this paper, the problem of controlling PWM single-phase AC/DC converters is addressed. The control objectives are twofold: (i) regulating the output voltage to a selected reference value, and (ii) ensuring a unitary power factor by forcing the grid ...
Y. Mchaouar   +7 more
doaj  

The zinc finger domains of PARP‐1 are selectively and potently inhibited by the Au(I)‐based drugs sodium aurothiomalate and aurothioglucose

open access: yesFEBS Letters, EarlyView.
PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley   +1 more source

New Operators for Aggregating Intuitionistic Fuzzy Information With Their Application in Decision Making

open access: yesIEEE Access, 2018
Aggregation of intuitionistic fuzzy information is a hot topic in Atanassov's intuitionistic fuzzy set theory, which has attracted much interest from researchers in recent years. In this paper, a series of new aggregation operators and weighted averaging
Cheng-Li Fan   +4 more
doaj   +1 more source

Numerical Artifacts in the Discontinuous Generalized Porous Medium Equation: How to Avoid Spurious Temporal Oscillations

open access: yes, 2018
Numerical discretizations of the Generalized Porous Medium Equation (GPME) with discontinuous coefficients are analyzed with respect to the formation of numerical artifacts.
Gerritsen, Margot   +2 more
core   +1 more source

On the theory of average case complexity

open access: yes[1989] Proceedings. Structure in Complexity Theory Fourth Annual Conference, 1992
The paper takes the next step in developing the theory of average case complexity initiated by L . A. Levin. A distributional decision problem is a pair \((D,\mu)\) where \(D\) is the set of strings and \(\mu\) is a (distribution) function from strings to the unit interval \([0,1]\).
Ben-David, Shai   +3 more
openaire   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Limit cycles for fourth-order autonomous differential equations

open access: yesElectronic Journal of Differential Equations, 2012
We provide sufficient conditions for the existence of periodic solutions of the fourth-order differential equation $$ ddddot x -(lambda+mu) dddot x +(1+lambda mu)ddot x -(lambda+mu)dot x+lambda mu x = varepsilon F(x, dot x, ddot x, dddot x ...
Jaume Llibre, Amar Makhlouf
doaj  

Addendum to Higher order stroboscopic averaged functions: a general relationship with Melnikov functions

open access: yesElectronic Journal of Qualitative Theory of Differential Equations
This addendum presents a relevant stronger consequence of the main theorem of the paper “Higher order stroboscopic averaged functions: a general relationship with Melnikov functions”, Electron. J. Qual. Theory Differ. Equ. 2021, No. 77.
Douglas Novaes
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

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