Results 61 to 70 of about 204,997 (308)

Inequality aversion in income, health, and income-related health.

Journal of Health Economics, 2020
Based on a survey of a sample of the general public, we estimate inequality aversion across income, health, and bivariate income-health. Inequality aversion is domain specific: mean inequality aversion is greater for income than for health, but the ...
J. Hurley, E. Mentzakis, M. Walli-Attaei
semanticscholar   +1 more source

Hederagenin Attenuates Morphine Addiction via GABAA1‐Mediated Modulation of Ca2+–CaMK–CREB Signaling in Ventral Tegmental Dopaminergic Neurons

Advanced Science, EarlyView.
Hederagenin is identified as a GABAA1‐targeting natural compound that suppresses morphine‐associated reward by restraining Ca2+–CaMK–cAMP–CREB signaling in ventral tegmental dopaminergic neurons. RVG29‐modified liposomal delivery further enhances brain accumulation and behavioral efficacy, providing a mechanistically defined strategy for natural ...
Hongyang Jiang, Ziting Zhou, Nannan Xue, Jiasi Deng, Yuanyuan Zhou, Xinying Lv, Yuxuan Wang, Yi Zhang, Haotian Pan, Geyan Xu, Yinkun Tao, Mengran Li, Xin Cui, Hongyue Ma, Qian Wang, Zhigang Lu   +15 more
wiley   +1 more source

Microcircuit mechanisms through which mediodorsal thalamic input to anterior cingulate cortex exacerbates pain-related aversion.

Neuron, 2019
SUMMARY Hyperexcitability of the anterior cingulate cortex (ACC) is thought to drive aversion associated with chronic neuropathic pain. Here we studied the contribution of input from mediodorsal thalamus (MD) to ACC, using sciatic nerve injury and ...
K. Meda, T. Patel, J. Bráz, Ruchi Malik, M. L. Turner, Helia Seifikar, A. Basbaum, V. Sohal   +7 more
semanticscholar   +1 more source

Persistent Zn2+ Influx‐Mediated Deacetylation of ANXA2 Regulates the “Zn2+‐Autophagic Flux” and Alleviates Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Zinc transporter SLC39A14 sustains intracellular Zn2+ levels to activate SIRT3‑dependent ANXA2 deacetylation at K302. This modification weakens ANXA2‑mTOR binding and releases autophagic‑flux suppression in nucleus pulposus cells. Dysregulated Zn2+ homeostasis disrupts this axis to drive intervertebral disc degeneration.
Yuxin Jin, Yongcheng Chen, Yihao Xie, Dongyang Hu, Longhui Gong, Zhihua Chen, Linjie Chen, Minhao Gao, Qizhu Chen, Morgan Jones, Hui Wang, Xiuling You, Kenny Yat Hong Kwan, Shoutao Weng, Taidong Lyu, Xiang Chen, Yuxiao Zhu, Yusheng Wang, Bin Li, Xiangyang Wang, Xiaofeng Jia, Kailiang Zhou, Ouqiang Wu, Aimin Wu   +23 more
wiley   +1 more source

Effects of wind turbines on area use and behaviour of semi-domestic reindeer in enclosures

Rangifer, 2004
In recent decades, industrial developments have expanded into reindeer ranges in the arctic and adjacent higher latitudes in search for energy, minerals, timber and other resources.
Kjetil Flydal, Sindre Eftestøl, Eigil Reimers, Jonathan E. Colman   +3 more
doaj   +1 more source

A Molecularly Defined Midbrain Circuit Mechanism for Sound‐Driven Defensive Behavior and Anxiety

Advanced Science, EarlyView.
Schematic diagram showing the Cbln2+ ICx–dPAG circuit for sound‐driven defensive and anxiety‐like behaviors. ABSTRACT The innate defense behaviors in response to threatening sounds play a fundamental role in survival. However, the neural circuits that detect threat‐relevant auditory cues and transform them into defensive behaviors remain poorly defined.
Jie Cao, Xingxing Lai, Lifang Huo, Zhouyuan Zheng, Qian Zhang, Zhimin Ye, Panpan Wan, Chao Ma, Congping Shang   +8 more
wiley   +1 more source

Ethanol Conditioned Taste Aversion in High Drinking in the Dark Mice

Brain Sciences, 2019
Two independent lines of High Drinking in the Dark (HDID-1, HDID-2) mice have been bred to reach high blood alcohol levels after a short period of binge-like ethanol drinking.
John C. Crabbe, Pamela Metten, Antonia M. Savarese, Angela R. Ozburn, Jason P. Schlumbohm, Stephanie E. Spence, Wyatt R. Hack   +6 more
doaj   +1 more source

How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services

Applied Economic Perspectives and Policy, EarlyView.
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang, Lena Kuhn, Hang Xiong, Zhanli Sun, Thomas Glauben   +4 more
wiley   +1 more source

The role of dorsal raphe nucleus neuropeptides in reward and aversion

Frontiers in Behavioral Neuroscience
The dorsal raphe nucleus is a critical node for affective and motivated circuits in the brain. Though typically known as a serotonergic hub, the dorsal raphe nucleus is also highly enriched in a variety of neuropeptides.
Kathryn Braden, Daniel C. Castro
doaj   +1 more source

RISK AVERSION BEHAVIOR. RELATIONSHIPS BETWEEN RISK AVERSION, PRUDENCE AND CAUTIOUSNESS [PDF]

This paper defines decreasing absolute risk aversion in purely behavioral termswithout any assumption of differentiability and shows that a strictly increasing and riskaverse utility function with decreasing absolute risk aversion is necessarily ...
Botoc Claudiu, Pirtea Marilen
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