Integrated one‐pot CRISPR‐Cas detection: Addressing strategies and future prospects
Integrated one‐pot CRISPR‐Cas detection significantly simplifies workflows, reduces cross‐contamination risks, and shortens turnaround times, making it highly suitable for point‐of‐care testing (POCT) and resource‐limited settings. Key challenges include system compatibility issues between Cas proteins and isothermal amplification, limited multiplexing
Jian Zhou +6 more
wiley +1 more source
Epidemiology of the highly pathogenic avian influenza H5N1 in Northern Vietnam: Applications for surveillance and control [PDF]
The epidemiology and the sanitary situation of avian influenza changed dramatically with the emergence of the highly pathogenic H5N1 virus (HPAI) in 1996. As a consequence, knowledge previously accumulated on the epidemiology and the ecology of the avian
Desvaux, Stéphanie, Desvaux, S.
core
Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir [PDF]
Ferrets are widely used to study human influenza virus infection. Their airway physiology and cell receptor distribution makes them ideal for the analysis of pathogenesis and virus transmission, and for testing the efficacy of anti-influenza ...
Dove, Brian K. +35 more
core +1 more source
Studies of Spanish influenza and encephalitis lethargica. [PDF]
PhDConcomitant with the Spanish influenza and extending to the 1920s encephalitis lethargica (EL), also termed von Economo's disease or sleepy sickness, occurred in epidemic proportion.
Lo, Lily Yen-Ching
core +4 more sources
Experiencing 50 Years of Synergistic Development in Structural Biology and Enzymology
Picture of Sunney Chan with Academia Sinica (AS) President James C. Liao and three Vice Presidents: Shin‐Kun Peng (left one), Tang K. Tang (right one), and Mei‐Yin Chou (right 2), taken at the annual Chinese New Year's Banquet of AS, February 7, 2025. This was likely Sunney's last appearance in formal activities of AS.
Ming‐Daw Tsai
wiley +1 more source
Glycyrrhizin exerts antioxidative effects in H5N1 influenza A virus-infected cells and inhibits virus replication and pro-inflammatory gene expression. [PDF]
Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1 ...
Michaelis, Martin +20 more
core +2 more sources
ABSTRACT Zoonotic infections caused by influenza A viruses (IAVs) of animal origin are a major public health concern, as they may represent the initial step toward the emergence of a pandemic strain. The host range of IAVs is shaped by species‐specific virus‐host interactions, and several host barriers have been identified that restrict the adaptation ...
Antoine Gerodez +13 more
wiley +1 more source
Pseudotype-based neutralization assays for influenza: a systematic analysis [PDF]
The use of vaccination against the influenza virus remains the most effective method of mitigating the significant morbidity and mortality caused by this virus.
Ferrara, Francesca +11 more
core +1 more source
Control of highly pathogenic avian influenza through vaccination
The stamping-out strategy has been used to control highly pathogenic avian influenza viruses in many countries, driven by the belief that vaccination would not be successful against such viruses and fears that avian influenza virus in vaccinated birds ...
Xianying Zeng +2 more
doaj +1 more source
Surveillance of Influenza A Virus and Its Subtypes in Migratory Wild Birds of Nepal. [PDF]
Nepal boarders India and China and all three countries lie within the Central Asian Flyway for migratory birds. Novel influenza A H7N9 caused human fatalities in China in 2013.
Dibesh Karmacharya +15 more
doaj +1 more source

