Results 11 to 20 of about 71,201 (184)
Infection of chicken embryo fibroblasts in vitro by avian sarcoma viruses results, beginning at about 36 hours after infection, in approximately a 5-fold increase in cellular levels of hyaluronic acid synthetase with a consequent increase in production ...
N. Ishimoto, H. Temin, J. Strominger
semanticscholar +2 more sources
Oncogenicity of non-transforming mutants of avian sarcoma viruses.
For practical purposes avian RNA tumour viruses have been divided into sarcoma and leukosis viruses. Sarcoma viruses have the ability to transform chick embryo fibroblasts in vitro and to induce fibro-sarcomas in vivo after a latent period of about 7 to 21 days. Leukosis viruses do not transform chick embryo fibroblasts, although they replicate in them,
P. Biggs, B. Milne, T. Graf, H. Bauer
semanticscholar +3 more sources
Avian Models for Human Carcinogenesis—Recent Findings from Molecular and Clinical Research [PDF]
Birds, especially the chick and hen, have been important biomedical research models for centuries due to the accessibility of the avian embryo and the early discovery of avian viruses. Comprehension of avian tumor virology was a milestone in basic cancer
Julia Niebora +15 more
doaj +2 more sources
Some biological properties of two new avian sarcoma viruses [PDF]
The new avian retroviruses UR1 and UR2 were isolated from spontaneous tumors of chickens by cocultivation of tumor material with susceptible chicken embryo fibroblasts. In vitro, UR1 induced formation of small foci of round and fusiform cells. On the other hand, cells infected by UR2 assumed an extremely elongated morphology.
P. Balduzzi +3 more
semanticscholar +3 more sources
Multi-clade co-evolution and differential replication efficiencies of subgroup A avian leukosis virus in Chinese guinea fowl [PDF]
Avian leukosis virus (ALV) has a wide range of hosts and is Susceptible to commercial chickens, local chickens and rare birds. To assess the presence of ALV-A infection in guinea fowl and characterize its viral genetics, PCR testing of guinea fowl ...
Jian Chen +8 more
doaj +2 more sources
Replication of avian sarcoma viruses in chicken macrophages.
Abstract Avian sarcoma viruses of subgroups B and C were able to replicate in chicken embryonic macrophages (derived from yolk sac) and in adult macrophages (obtained from peripheral blood), while avian sarcoma viruses of subgroups A and D were not.
L. Gazzolo, M. Moscovici, C. Moscovici
semanticscholar +4 more sources
Exploring the Microbial Community Structure in the Chicken House Environment by Metagenomic Analysis
The environmental conditions of chicken houses play an important role in the growth and development of these animals. The chicken house is an essential place for the formation of microbial aerosols. Microbial aerosol pollution and transmission can affect
Cheng Lou +5 more
doaj +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
Innovative Chorioallantoic Membrane Model as Valuable Tool in Diagnostics and Testing of Domestic Animal Cancers. [PDF]
In recent years, particular attention has been paid to the possible connections, similarities, and potential uses of animals, especially pets (dogs and cats), in research on the causes, characteristics, and treatment of cancers occurring in pets and humans. One of the most promising experimental research models used to explore these issues is the avian
Sczasny A +3 more
europepmc +2 more sources
The Genus Alpharetrovirus contains viruses pathogenic mainly for chickens, forming the Avian Sarcoma and Leukosis Virus group (ASLV). Cells of most Galliform species, besides chickens, contain genetic elements (endogenous retroviruses, ERVs) that could ...
Sergio Fandiño +3 more
doaj +1 more source

