Results 21 to 30 of about 14,987 (195)
The Importance of Being Non-Defective: A Mini Review Dedicated to the Memory of Jan Svoboda
Jan Svoboda triggered investigations on non-defective avian sarcoma viruses. These viruses were a critical factor in the genetic understanding of retroviruses.
Peter K. Vogt
doaj +1 more source
Plaque assay of avian sarcoma viruses using casein [PDF]
The caseinolytic activity of several strains of Rous sarcoma virus (RSV), conditional and nonconditional mutants of RSV, and nontransforming avian leukosis viruses was investigated. Only those viruses capable of transforming chick fibroblasts in vitro induced lysis of casein incorporated into an agar overlay.
P C, Balduzzi, H, Murphy
openaire +2 more sources
Synthesis of IFN-β by Virus-Infected Chicken Embryo Cells Demonstrated with Specific Antisera and a New Bioassay [PDF]
Transcripts of interferon-α(IFN-α) and IFN-β genes are present in virus-infected chicken cells, but because of a lack of appropriate assays and reagents, it was unclear if biologically active IFN-β is secreted.
Harlin, Olof +4 more
core +1 more source
Proposal for Numbering Mutants of Avian Leukosis and Sarcoma Viruses [PDF]
A system for the numbering of mutants of avian sarcoma and leukosis viruses is proposed.
P K, Vogt, R A, Weiss, H, Hanafusa
openaire +2 more sources
Cell Transformation by RNA Viruses: An Overview
Studies of oncogenic viruses have made seminal contributions to the molecular biology of cancer. Key discoveries include the identification of viral oncogenes and cellular proto-oncogenes, elucidation of signal transduction pathways, and identification ...
Hung Fan
doaj +1 more source
Multifunctional miR-155 Pathway in Avian Oncogenic Virus-Induced Neoplastic Diseases
MicroRNAs (miRNAs) are small noncoding RNAs that fine-tune the responses of the cell by modulating the cell transcriptome and gene expression. MicroRNA 155 (miR-155) is a conserved multifunctional miRNA involved in multiple roles including the modulation
Megha Sravani Bondada +2 more
doaj +1 more source
Domestic chickens activate a piRNA defense against avian leukosis virus [PDF]
PIWI-interacting RNAs (piRNAs) protect the germ line by targeting transposable elements (TEs) through the base-pair complementarity. We do not know how piRNAs co-evolve with TEs in chickens.
Anai +124 more
core +2 more sources
Viruses and the cellular RNA decay machinery. [PDF]
The ability to control cellular and viral gene expression, either globally or selectively, is central to a successful viral infection, and it is also crucial for the host to respond and eradicate pathogens.
Gaglia, Marta, Glaunsinger, Britt
core +1 more source
Innate antiviral immunity establishes first line of defense against invading pathogens through sensing their molecular structures such as viral RNA. This antiviral potential of innate immunity is mainly attributed to a myriad of IFN-stimulated genes ...
Mohammed A. Rohaim +7 more
doaj +1 more source
Cytokines of Birds: Conserved Functions [PDF]
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F. +4 more
core +1 more source

