Avian Models for Human Carcinogenesis—Recent Findings from Molecular and Clinical Research [PDF]
CellsBirds, especially the chick and hen, have been important biomedical research models for centuries due to the accessibility of the avian embryo and the early discovery of avian viruses. Comprehension of avian tumor virology was a milestone in basic cancer
Julia Niebora +15 more
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Multi-clade co-evolution and differential replication efficiencies of subgroup A avian leukosis virus in Chinese guinea fowl [PDF]
BMC Veterinary ResearchAvian leukosis virus (ALV) has a wide range of hosts and is Susceptible to commercial chickens, local chickens and rare birds. To assess the presence of ALV-A infection in guinea fowl and characterize its viral genetics, PCR testing of guinea fowl ...
Jian Chen +8 more
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Replication of avian sarcoma viruses in chicken macrophages
Virology, 1974 Abstract Avian sarcoma viruses of subgroups B and C were able to replicate in chicken embryonic macrophages (derived from yolk sac) and in adult macrophages (obtained from peripheral blood), while avian sarcoma viruses of subgroups A and D were not.
L Gazzolo, C Moscovici, M G Moscovici
exaly +4 more sources
Exploring the Microbial Community Structure in the Chicken House Environment by Metagenomic Analysis
Animals, 2023 The environmental conditions of chicken houses play an important role in the growth and development of these animals. The chicken house is an essential place for the formation of microbial aerosols. Microbial aerosol pollution and transmission can affect
Cheng Lou +5 more
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c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
Microorganisms, 2023 The Genus Alpharetrovirus contains viruses pathogenic mainly for chickens, forming the Avian Sarcoma and Leukosis Virus group (ASLV). Cells of most Galliform species, besides chickens, contain genetic elements (endogenous retroviruses, ERVs) that could ...
Sergio Fandiño +3 more
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CRISPR/Cas9 Editing of Viral Receptors and Biotechnological Approach to Host Resistance
Proceedings, 2020 Avian sarcoma and leukosis virus (ASLV), diversified into seven phylogenetically relativesubgroups (A, B, C, D, E, J, and K), present as either exogenous or endogenous viruses in domesticchicken. [...]
Jiří Hejnar +7 more
doaj +1 more source
Innovative Chorioallantoic Membrane Model as Valuable Tool in Diagnostics and Testing of Domestic Animal Cancers. [PDF]
Transbound Emerg DisIn recent years, particular attention has been paid to the possible connections, similarities, and potential uses of animals, especially pets (dogs and cats), in research on the causes, characteristics, and treatment of cancers occurring in pets and humans. One of the most promising experimental research models used to explore these issues is the avian
Sczasny A +3 more
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Imaging single retrovirus entry through alternative receptor isoforms and intermediates of virus-endosome fusion. [PDF]
PLoS Pathogens, 2011 A large group of viruses rely on low pH to activate their fusion proteins that merge the viral envelope with an endosomal membrane, releasing the viral nucleocapsid.
Naveen K Jha +8 more
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Oncogenicity of avian leukosis viruses of different subgroups and of mutants of sarcoma viruses [PDF]
Infection and Immunity, 1977 Leukosis viruses of seven subgroups were tested for oncogenicity in chickens susceptible to virus infection and to development of lymphoid leukosis (LL) tumors. All subgroup A viruses and the subgroup B virus tested produced a high incidence of LL and other related neoplasms.
H G, Purchase +5 more
openaire +2 more sources