Results 11 to 20 of about 8,766 (148)
The Importance of Being Non-Defective: A Mini Review Dedicated to the Memory of Jan Svoboda
Jan Svoboda triggered investigations on non-defective avian sarcoma viruses. These viruses were a critical factor in the genetic understanding of retroviruses.
Peter K. Vogt
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Plaque assay of avian sarcoma viruses using casein [PDF]
The caseinolytic activity of several strains of Rous sarcoma virus (RSV), conditional and nonconditional mutants of RSV, and nontransforming avian leukosis viruses was investigated. Only those viruses capable of transforming chick fibroblasts in vitro induced lysis of casein incorporated into an agar overlay.
P C, Balduzzi, H, Murphy
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Proposal for Numbering Mutants of Avian Leukosis and Sarcoma Viruses [PDF]
A system for the numbering of mutants of avian sarcoma and leukosis viruses is proposed.
P K, Vogt, R A, Weiss, H, Hanafusa
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Cell Transformation by RNA Viruses: An Overview
Studies of oncogenic viruses have made seminal contributions to the molecular biology of cancer. Key discoveries include the identification of viral oncogenes and cellular proto-oncogenes, elucidation of signal transduction pathways, and identification ...
Hung Fan
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Multifunctional miR-155 Pathway in Avian Oncogenic Virus-Induced Neoplastic Diseases
MicroRNAs (miRNAs) are small noncoding RNAs that fine-tune the responses of the cell by modulating the cell transcriptome and gene expression. MicroRNA 155 (miR-155) is a conserved multifunctional miRNA involved in multiple roles including the modulation
Megha Sravani Bondada +2 more
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Innate antiviral immunity establishes first line of defense against invading pathogens through sensing their molecular structures such as viral RNA. This antiviral potential of innate immunity is mainly attributed to a myriad of IFN-stimulated genes ...
Mohammed A. Rohaim +7 more
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Background Retrovirus infection depends on binding of the retroviral envelope (Env) protein to specific cell-surface protein receptors. Interference, or superinfection resistance, is a frequent consequence of retroviral infection, and occurs when newly ...
Van Hoeven Neal S, Miller A
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The initial step of retrovirus entry—the interaction between the virus envelope glycoprotein trimer and a cellular receptor—is complex, involving multiple, noncontiguous determinants in both proteins that specify receptor choice, binding ...
Mark J. Federspiel
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The subgroup A through E avian sarcoma and leukosis viruses ASLV(A) through ASLV(E) are a group of highly related alpharetroviruses that have evolved to use very different host protein families as receptors. We have exploited genetic selection strategies
Xueqian Yin +4 more
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Binding of more than one Tva800 molecule is required for ASLV-A entry
Background Understanding the mechanism by which viruses enter their target cell is an essential part of understanding their infectious cycle. Previous studies have focussed on the multiplicity of viral envelope proteins that need to bind to their cognate
Gray Eleanor R +3 more
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