Results 31 to 40 of about 8,766 (148)

Integumentary fibrosarcoma in a free‐living swan (Cygnus olor): Medical and welfare considerations

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 10‐kg adult male mute swan (Cygnus olor) of unknown age was admitted for investigations of two large ventral masses overlying the keel bone, which were discharging purulent material. The masses measured 8.9 × 2.1 cm and 4.2 × 3.2 cm. Empirical treatment with non‐steroidal anti‐inflammatory drugs and antimicrobials was instigated.
Rachael Amy McKinney, Katherine Hughes
wiley   +1 more source

AP‐1‐Targeting Decoy Oligonucleotides: Mechanisms and Therapeutic Potential as Modulators of Inflammatory Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Numerous cellular functions, such as apoptosis, proliferation, differentiation, survival, transformation and cell migration, are regulated by a crucial transcription factor called activator protein 1 (AP‐1). Growing evidence indicates that AP‐1 is involved in severe conditions like fibrosis, cancer, and organ damage, as well as inflammatory ...
Maryam Mahjoubin‐Tehran, Samaneh Rezaei, Vasily N. Sukhorukov, Amin Jalili, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Integrative Approaches to Treating Cellular Senescence in Kidney Disease

Advanced Science, Volume 13, Issue 21, 13 April 2026.
ABSTRACT Cellular senescence in the kidney plays a crucial role in the progression of acute kidney injury and chronic kidney disease. Therapeutic approaches targeting senescent cells, such as small molecule senolytic and senomorphic drugs, display efficacy in preclinical models.
Tomoka Misawa, Amruta A, LaTonya J. Hickson, Joy Wolfram   +3 more
wiley   +1 more source

Infection Risk From Humans and Animals in the Anatomy Laboratory: A Scoping Review

Clinical Anatomy, Volume 39, Issue 3, Page 346-367, April 2026.
ABSTRACT Whole‐body dissection is a cornerstone of anatomy education. During and following the COVID‐19 pandemic, exposure to infectious agents and other risks of dissection were highlighted. To identify potential risks, one must have the data outlining these risks in specific situations.
Margaret A. McNulty, Elizabeth R. Agosto
wiley   +1 more source

Role of PQBP1 in Pathogen Recognition—Impact on Innate Immunity

Viruses
The intrinsically disordered polyglutamine-binding protein 1 (PQBP1) has been linked to various cellular processes including transcription, alternative splicing, translation and innate immunity.
Lukas Wiench, Domenico Rizzo, Zora Sinay, Zsófia Nacsa, Nina V. Fuchs, Renate König   +5 more
doaj   +1 more source

Influenza virus infection drives upregulation of CD84 across a broad range of immune cells

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Our findings reveal a link between high CD84 expression in humans and recovery from respiratory viral infections. In influenza virus‐infected mice, CD84 is upregulated on a broad range of innate and adaptive immune cell populations, particularly on activated and influenza virus‐specific T‐cell populations and associated with less disease severity ...
Xiaoxiao Jia, Isabelle JH Foo, Hayley A McQuilten, Jeremy Chase Crawford, Aira F Cabug, Deborah Gebregzabher, Janet Chou, Robert C Mettelman, Tanya Novak, Lee‐Ann Van de Velde, Ryan S Thwaites, Adrienne G Randolph, Paul G Thomas, Jianqing Xu, Zhongfang Wang, Katherine Kedzierska, Lukasz Kedzierski, Brendon Y Chua   +17 more
wiley   +1 more source

Plasma proteomic profiling and molecular clustering reveal immune‐defined prognostic subtypes in lung adenocarcinoma

International Journal of Cancer, Volume 158, Issue 4, Page 858-865, 15 February 2026.
What's new? Lung adenocarcinoma shows considerable heterogeneity in disease progression and therapeutic response. Here, the authors analyzed tumor samples through proteomic profiling and applied network‐based clustering. They identified two distinct patient groups with different demographic, clinical, and molecular characteristics.
Ujjwal Neogi, Anoop T. Ambikan, Kati Turkowski, Marc A. Schneider, Vanessa M. Beutgen, Johannes Graumann, Hauke Winter, Marek Bartkuhn, Werner Seeger, Soni S. Pullamsetti, Rajkumar Savai   +10 more
wiley   +1 more source

Assessing the validity of leucine zipper constructs predicted by AlphaFold

Protein Science, Volume 35, Issue 1, January 2026.
Abstract AP‐1 transcription factors are a network of cellular regulators that combine in different dimer pairs to control a range of pathways involved in differentiation, growth, and cell death. They dimerize via leucine zipper coiled‐coil domains that are preceded by a basic DNA binding domain.
Isobel Mitic, Keiran Rowell, Thomas Litfin, Katharine A. Michie, David A. Jacques   +4 more
wiley   +1 more source

Ultrastructure of the Surfaces of Cells Infected with Avian Leukosis-Sarcoma Viruses [PDF]

Journal of Virology, 1968
When stained with ruthenium red (RR), chick embryo cells infected with various strains of Rous sarcoma virus (RSV) and with avian leukosis viruses RAV-1 and RAV-3 showed an increase in the layer of acid mucopolysaccharides (AMPS) at their surfaces as compared with uninfected cells.
openaire   +2 more sources

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source