Results 31 to 40 of about 14,987 (195)

The effect of helper virus on Abelson virus-induced transformation of lymphoid cells [PDF]

open access: yes, 1978
Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses.
Baltimore, David, Rosenberg, Naomi
core   +2 more sources

Use of different but overlapping determinants in a retrovirus receptor accounts for non-reciprocal interference between xenotropic and polytropic murine leukemia viruses

open access: yesRetrovirology, 2005
Background Retrovirus infection depends on binding of the retroviral envelope (Env) protein to specific cell-surface protein receptors. Interference, or superinfection resistance, is a frequent consequence of retroviral infection, and occurs when newly ...
Van Hoeven Neal S, Miller A
doaj   +1 more source

m6a RNA methylation: the implications for health and disease [PDF]

open access: yes, 2014
The recent resurgence of interest in m6a has been spurred by some intriguing findings detailing the effects and dynamics of this epigenetic modification.
McGuinness, D., Mcguinness, D.H.
core   +1 more source

Reverse Engineering Provides Insights on the Evolution of Subgroups A to E Avian Sarcoma and Leukosis Virus Receptor Specificity

open access: yesViruses, 2019
The initial step of retrovirus entry—the interaction between the virus envelope glycoprotein trimer and a cellular receptor—is complex, involving multiple, noncontiguous determinants in both proteins that specify receptor choice, binding ...
Mark J. Federspiel
doaj   +1 more source

Search for virus specific DNA sequences and viral particles in mitochondria of avian leukemic myeloblasts [PDF]

open access: yes, 1977
The intracellular localization of the avian myeloblastosis virus (AMV) genome was studied. Nuclear and mitochondrial DNAs from myeloblasts were examined by hybridization with 32P labeled AMV-RNA of high molecular weight for the presence of virus specific
Oda, Takuzo, Ogura, Hajime
core   +1 more source

Mutations in Both the Surface and Transmembrane Envelope Glycoproteins of the RAV-2 Subgroup B Avian Sarcoma and Leukosis Virus Are Required to Escape the Antiviral Effect of a Secreted Form of the TvbS3 Receptor

open access: yesViruses, 2019
The subgroup A through E avian sarcoma and leukosis viruses ASLV(A) through ASLV(E) are a group of highly related alpharetroviruses that have evolved to use very different host protein families as receptors. We have exploited genetic selection strategies
Xueqian Yin   +4 more
doaj   +1 more source

Binding of more than one Tva800 molecule is required for ASLV-A entry

open access: yesRetrovirology, 2011
Background Understanding the mechanism by which viruses enter their target cell is an essential part of understanding their infectious cycle. Previous studies have focussed on the multiplicity of viral envelope proteins that need to bind to their cognate
Gray Eleanor R   +3 more
doaj   +1 more source

IFNα and IFNγ Impede Marek’s Disease Progression [PDF]

open access: yes, 2019
Marek’s disease virus (MDV) is an alphaherpesvirus that causes Marek’s disease, a malignant lymphoproliferative disease of domestic chickens. While MDV vaccines protect animals from clinical disease, they do not provide sterilizing immunity and allow ...
Bertzbach, Luca D.   +6 more
core   +1 more source

Alpharetroviral Vectors: From a Cancer-Causing Agent to a Useful Tool for Human Gene Therapy [PDF]

open access: yes, 2014
Gene therapy using integrating retroviral vectors has proven its effectiveness in several clinical trials for the treatment of inherited diseases and cancer.
Labenski, Verena   +2 more
core   +2 more sources

Avian Sarcoma and Leukosis Virus Envelope Glycoproteins Evolve to Broaden Receptor Usage Under Pressure from Entry Competitors

open access: yesViruses, 2019
The subgroup A through E avian sarcoma and leukosis viruses (ASLV(A) through ASLV(E)) are a group of highly related alpharetroviruses that have evolved their envelope glycoproteins to use different receptors to enable efficient virus entry due to host ...
Audelia Munguia, Mark J. Federspiel
doaj   +1 more source

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