Results 51 to 60 of about 14,987 (195)

Some biological properties of two new avian sarcoma viruses [PDF]

Journal of Virology, 1981
The new avian retroviruses UR1 and UR2 were isolated from spontaneous tumors of chickens by cocultivation of tumor material with susceptible chicken embryo fibroblasts. In vitro, UR1 induced formation of small foci of round and fusiform cells. On the other hand, cells infected by UR2 assumed an extremely elongated morphology.
P C, Balduzzi, M F, Notter, H R, Morgan, M, Shibuya   +3 more
openaire   +2 more sources

RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging

Biological Reviews, EarlyView.
ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad, Suresha G. Prabhu, Lizna M. Ali, Vineeta N. Pillai, Farah Mustafa, Tahir A. Rizvi   +5 more
wiley   +1 more source

Characterization of endonuclease activities in Moloney murine leukemia virus and its replication-defective mutants [PDF]

, 1987
To study Moloney murine leukemia virus (M-MulV) proteins associated with the integration of proviral DNA into the host chromosome, we isolated endonuclease activities from purified virion preparations of the wild type and two of its replication mutants ...
Baltimore, David, Panet, Amos
core  

Use of single-chain antibody derivatives for targeted drug delivery [PDF]

, 2016
Single-chain antibodies (scFvs), which contain only the variable domains of full-length antibodies, are relatively small molecules that can be used for selective drug delivery.
Ahmadzadeh, V., Erfani-Moghadam, V., Jaliani, H.Z., Khalili, M., Safdari, Y., Zarei, V.   +5 more
core   +1 more source

Berberine alleviates pyroptosis of retinal ganglion cells in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Heteroduplex analysis of the RNA of clone 3 Moloney murine sarcoma virus [PDF]

, 1979
Heteroduplex analysis of the RNA isolated from purified virions of clone 3 Moloney murine sarcoma virus (M-MSV) hybridized to cDNA's from Moloney murine leukemia virus (M-MLV) and clone 124 M-MSV shows that the main physical component of clone 3 RNA is ...
Chen, Yueh-Hsiu, Davidson, Norman, Duesberg, P. H., Verma, Inder M.   +3 more
core  

New human transforming genes detected by a tumorigenicity assay [PDF]

, 1984
A sensitive bioassay for transforming genes based on the tumorigenicity of cotransfected NIH3T3 cells in nude mice was developed. The assay differs substantially from the NIH3T3 focus assay.
Fasano, O., Birnbaum, D., Edlund, L., Fogh, J., Wigler, M. H.   +4 more
core   +1 more source

Oxidative Stress in the Tumor Immune Microenvironment: Mechanisms and Therapeutic Perspectives

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oxidative stress is involved in several key processes in cancer, including redox regulation, DNA damage, post‐translational modifications, transcriptional regulation, epigenetic modifications, metabolic reprogramming, cell death, and immune modulation. These mechanisms collectively influence tumor progression, immune evasion, and therapeutic responses,
Zhen Wang, Bowen Li, Pan Tang, Fanchen Yan, Shuxin Wang, Guiying Leng, Panduo Dawa, Yuansi Chen, Yihan Guo, Pan Yang, Yi Li, Siyu Liu, Erdan Dong, Siyuan Qin, Zhoufeng Wang   +14 more
wiley   +1 more source

Modernising epidemic science: enabling patient-centred research during epidemics [PDF]

, 2016
Background: Emerging and epidemic infectious disease outbreaks are a significant public health problem and global health security threat. As an outbreak begins, epidemiological investigations and traditional public health responses are generally mounted ...
Horby, Peter W., Rojek, Amanda M.
core   +3 more sources

Integumentary fibrosarcoma in a free‐living swan (Cygnus olor): Medical and welfare considerations

Veterinary Record Case Reports, Volume 14, Issue 2, May 2026.
Abstract A 10‐kg adult male mute swan (Cygnus olor) of unknown age was admitted for investigations of two large ventral masses overlying the keel bone, which were discharging purulent material. The masses measured 8.9 × 2.1 cm and 4.2 × 3.2 cm. Empirical treatment with non‐steroidal anti‐inflammatory drugs and antimicrobials was instigated.
Rachael Amy McKinney, Katherine Hughes
wiley   +1 more source