Results 71 to 80 of about 14,987 (195)

Interplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus [PDF]

open access: yes, 2015
Retroviruses are positive-sense, single-stranded RNA viruses that reverse transcribe their RNA genomes into double-stranded DNA for integration into the host cell chromosome.
Breanna L. Rice   +4 more
core   +2 more sources

Assessing the validity of leucine zipper constructs predicted by AlphaFold

open access: yesProtein Science, Volume 35, Issue 1, January 2026.
Abstract AP‐1 transcription factors are a network of cellular regulators that combine in different dimer pairs to control a range of pathways involved in differentiation, growth, and cell death. They dimerize via leucine zipper coiled‐coil domains that are preceded by a basic DNA binding domain.
Isobel Mitic   +4 more
wiley   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

open access: yesSmall Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N   +2 more
wiley   +1 more source

Ultrastructure of the Surfaces of Cells Infected with Avian Leukosis-Sarcoma Viruses [PDF]

open access: yesJournal of Virology, 1968
When stained with ruthenium red (RR), chick embryo cells infected with various strains of Rous sarcoma virus (RSV) and with avian leukosis viruses RAV-1 and RAV-3 showed an increase in the layer of acid mucopolysaccharides (AMPS) at their surfaces as compared with uninfected cells.
openaire   +2 more sources

Cryptococcal Osteomyelitis in a Virally Suppressed Adolescent Living With HIV: A Case Report

open access: yesCase Reports in Infectious Diseases, Volume 2026, Issue 1, 2026.
Cryptococcal neoformans infection of the central nervous system (CNS) is well‐documented in Sub‐Saharan Africa due to its association with the human immunodeficiency virus (HIV) pandemic. While cryptococcal infections can occur at sites other than the CNS, such as in the bones, these instances are less common and have been inadequately documented in ...
Linda A. Mandikiyana Chirimuta   +6 more
wiley   +1 more source

Immunologic Aspects of Leukemia Virus Research in Humans [PDF]

open access: yes, 1973
Author Institution: Department of Veterinary Pathobiology, The Ohio State UniversityRecent theory concerning the mechanisms by which RNA-tumor viruses are transmitted in animals and their genetic information expressed during embryogenesis and adulthood ...
Yohn, David S.
core  

Vírus causadores de câncer e o papel da medicina laboratorial: revisão de literatura e perspectivas [PDF]

open access: yes, 2013
Cancer-causing viruses are responsible for up to 20% of cancers with infectious etiology, representing a serious public health problem worldwide. Since the discovery of the first human cancer-causing virus, several others have been associated with ...
Granato, Celso Francisco Hernandes   +1 more
core   +3 more sources

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon   +8 more
wiley   +1 more source

Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]

open access: yes, 2001
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers   +12 more
core   +1 more source

Brain‐Wide Connectivity Patterns of Feedforward and Feedback Cortico‐Cortical Neurons in the Mouse Secondary Visual Cortex

open access: yesJournal of Comparative Neurology, Volume 533, Issue 12, December 2025.
Using projection‐ and layer‐specific rabies tracing, we mapped brain‐wide inputs to multiple feedforward and feedback neuron types in VISl (LM), the mouse secondary visual cortex. Although input patterns were broadly similar across neuron types, we observed differences in the relative contributions of visual, retrosplenial, and auditory cortices ...
Richard G. Dickson   +6 more
wiley   +1 more source

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