Results 71 to 80 of about 14,987 (195)
Interplay between the alpharetroviral Gag protein and SR proteins SF2 and SC35 in the nucleus [PDF]
Retroviruses are positive-sense, single-stranded RNA viruses that reverse transcribe their RNA genomes into double-stranded DNA for integration into the host cell chromosome.
Breanna L. Rice +4 more
core +2 more sources
Assessing the validity of leucine zipper constructs predicted by AlphaFold
Abstract AP‐1 transcription factors are a network of cellular regulators that combine in different dimer pairs to control a range of pathways involved in differentiation, growth, and cell death. They dimerize via leucine zipper coiled‐coil domains that are preceded by a basic DNA binding domain.
Isobel Mitic +4 more
wiley +1 more source
Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N +2 more
wiley +1 more source
Ultrastructure of the Surfaces of Cells Infected with Avian Leukosis-Sarcoma Viruses [PDF]
When stained with ruthenium red (RR), chick embryo cells infected with various strains of Rous sarcoma virus (RSV) and with avian leukosis viruses RAV-1 and RAV-3 showed an increase in the layer of acid mucopolysaccharides (AMPS) at their surfaces as compared with uninfected cells.
openaire +2 more sources
Cryptococcal Osteomyelitis in a Virally Suppressed Adolescent Living With HIV: A Case Report
Cryptococcal neoformans infection of the central nervous system (CNS) is well‐documented in Sub‐Saharan Africa due to its association with the human immunodeficiency virus (HIV) pandemic. While cryptococcal infections can occur at sites other than the CNS, such as in the bones, these instances are less common and have been inadequately documented in ...
Linda A. Mandikiyana Chirimuta +6 more
wiley +1 more source
Immunologic Aspects of Leukemia Virus Research in Humans [PDF]
Author Institution: Department of Veterinary Pathobiology, The Ohio State UniversityRecent theory concerning the mechanisms by which RNA-tumor viruses are transmitted in animals and their genetic information expressed during embryogenesis and adulthood ...
Yohn, David S.
core
Vírus causadores de câncer e o papel da medicina laboratorial: revisão de literatura e perspectivas [PDF]
Cancer-causing viruses are responsible for up to 20% of cancers with infectious etiology, representing a serious public health problem worldwide. Since the discovery of the first human cancer-causing virus, several others have been associated with ...
Granato, Celso Francisco Hernandes +1 more
core +3 more sources
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon +8 more
wiley +1 more source
Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers +12 more
core +1 more source
Using projection‐ and layer‐specific rabies tracing, we mapped brain‐wide inputs to multiple feedforward and feedback neuron types in VISl (LM), the mouse secondary visual cortex. Although input patterns were broadly similar across neuron types, we observed differences in the relative contributions of visual, retrosplenial, and auditory cortices ...
Richard G. Dickson +6 more
wiley +1 more source

