Results 51 to 60 of about 84,978 (308)

Readmissions and Mortality During the First Year After Stroke—Data From a Population-Based Incidence Study

Frontiers in Neurology, 2020
Background: After a first-ever-in-a-lifetime stroke (FELS), hospital readmissions are common and associated with increased mortality and morbidity of stroke survivors, thus, raising the overall health burden of stroke.
Pedro Abreu, Pedro Abreu, Rui Magalhães, Diana Baptista, Elsa Azevedo, Elsa Azevedo, Maria Carolina Silva, Manuel Correia, Manuel Correia   +8 more
doaj   +1 more source

Trend of preventable neonatal mortality in the States of Brazil

Revista Brasileira de Saúde Materno Infantil, 2021
Objectives: to describe the trend of preventable neonatal mortality due to interventions by the Unified Health System in Brazil from 2000 to 2018, according to groups of causes of death and maternal residence. Methods: mixed ecological study with data
Kelly Holanda Prezotto, Rosana Rosseto de Oliveira, Sandra Marisa Pelloso, Carlos Alexandre Molena Fernandes   +3 more
doaj   +2 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

The gap in life expectancy and lifespan inequality between Iran and neighbour countries: the contributions of avoidable causes of death

International Journal for Equity in Health, 2022
Background Healthcare system and intersectoral public health policies play a crucial role in improving population health and reducing health inequalities.
Kasim Allel, Mohammad Hajizadeh, Ali Kiadaliri   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Avoidable Mortality in Korea 1997–2001: Temporal Trend and its Contribution to All-cause Mortality

International Journal of Public Health
ObjectiveThis study analyzed the mortality trends from avoidable causes in Korea from 1997 to 2021, to estimate its contribution to the overall mortality in different subgroups, including.
Yoolwon Jeong, Sunghyo Seo
doaj   +1 more source

Avoidable Mortality: The Core of the Global Cancer Divide

Journal of Global Oncology, 2018
Purpose: The incidence of infection-associated cancers and lethality of cancers amenable to treatment are closely correlated with the income of countries. We analyzed a core part of this global cancer divide—the distribution of premature mortality across
Felicia Marie Knaul, Hector Arreola-Ornelas, Natalia M. Rodriguez, Oscar Méndez-Carniado, Xiaoxiao Jiang Kwete, Esteban Puentes-Rosas, Afsan Bhadelia   +6 more
doaj   +1 more source

Direct and lost productivity costs associated with avoidable hospital admissions

BMC Health Services Research, 2020
Background Hospitalizations for ambulatory care sensitive conditions are commonly used to evaluate primary health care performance, as the hospital admission could be avoided if care was timely and adequate.
João Victor Muniz Rocha, Ana Patrícia Marques, Bruno Moita, Rui Santana   +3 more
doaj   +1 more source