Results 71 to 80 of about 84,978 (308)
Avoidable factors in child death. [PDF]
Archives of Disease in Childhood, 1983 There were 131 deaths among children aged between birth and 14 years during a period of 18 months in one inner London area health authority. One hundred children died in hospital, 23 at home, and 8 elsewhere. Thirty three died of congenital, 46 of perinatal, and 34 of other medical causes.
Y, Sherman, D J, Matthew, R D, Boyd
openaire +2 more sources
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Avoidable mortality across Canada from 1975 to 1999
BMC Public Health, 2006 Background The concept of 'avoidable' mortality (AM) has been proposed as a performance measure of health care systems. In this study we examined mortality in five geographic regions of Canada from 1975 to 1999 for previously defined avoidable disease ...
James Paul D, Manuel Doug G, Mao Yang
doaj +1 more source
BMC Health Services Research, 2021 Background Little is known about the nature of patients’ transitions between healthcare settings in the last year of life (LYOL) in Germany. Patients often experience transitions between different healthcare settings, such as hospitals and long-term ...
Alina Kasdorf +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Avoidable Mortality Risks and Measurement of Wellbeing and Inequality [PDF]
This paper proposes a data envelopment method to separate avoidable and unavoidable mortality risks. As unavoidable mortality is the result of nature, only avoidable mortality is of relevance in measuring wellbeing and inequality.
K.K.Tang, Prasada Rao
core
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Some reasons for lowering the legal drink-drive limit in Britain [PDF]
, 2005 The current legal limit on drivers? blood alcohol content was set at 80mg/100ml nearly 40years ago and there are now only two other Member States of the European Union, both ofthem small countries, with limits higher than 50mg/100ml.
Allsop, RE
core
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source