Results 41 to 50 of about 2,898,126 (296)
The axial capacity of driven piles in clay
, 1987 An instrumented model pile was used to investigate the fundamental behaviour in clay soils of driven cylindrical steel piles used for offshore structures. Four test-bed sites were chosen; two in stiff heavily consolidated clays, and two in normally/lightly overconsolidated clays.
Coop, M, Coop, M. R.
openaire +2 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Buildings, 2022 Axial bearing capacity is the key index of circular concrete-filled steel tubes (CCFST). A hybrid PSO-ANN model consisting of an artificial neural network (ANN) optimized with particle swarm algorithm (PSO) was proposed to reliably and accurately predict
Xuerui Liu, Yanqi Wu, Yisong Zhou
doaj +1 more source
The influence of axial misalignment on the load‐bearing capacity of buttwelded joints
ce/papers, 2023 Abstract Steel structures in Europe are generally designed and dimensioned according to EN 1993. The execution, in turn, is carried out according to EN 1090‐2, which for the evaluation of welded joints refers to the quality levels of EN ISO 5817.
Voelkel, Justus Viktor Johannes +2 more
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Deep Learning-Based Prediction of the Axial Capacity of CFRP-Strengthened Concrete Columns
InfrastructuresFiber-reinforced polymer (FRP) composites are widely used to strengthen reinforced concrete (RC) columns due to their high strength, durability, and ease of installation.
Nasim Shakouri Mahmoudabadi +2 more
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Effect of Helical Geometry on the Axial Compressive Capacity
International Journal of Innovative Science and Research Technology, 2020 Helical pile is an invention in pile foundation with a main objective of increasing pile capacity. According to Prasad, et.al (1996), definition of helical pile is a pile foundation that equipped with one or more helix that has a round shape, attached to the shaft with a certain distance between helixes.
Yofy Kurniawan +2 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source