Results 61 to 70 of about 2,898,126 (296)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Design and Experimental Validation of a Ducted Counter-rotating Axial-flow Fans System [PDF]

, 2012
An experimental study on the design of counter-rotating axial-flow fans was carried out. The fans were designed using an inverse method. In particular, the system is designed to have a pure axial discharge flow.
NOURI, Hussain, BAKIR, Farid, RAVELET, Florent, REY, Robert, F. Bakir, R. Rey, H. Nouri, F. Ravelet, SARRAF, Christophe, C. Sarraf   +9 more
core   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Performance of Round-Ended Concrete-Filled Steel Tubular Columns Under Combined Compression–Bending–Shear Loading

Buildings
This study develops and validates a finite element model for round-ended concrete-filled steel tubular (CFST) columns subjected to combined compression–bending–shear loading using ABAQUS.
Yan Peng, Junfeng Liu, Junping He, Zongfeng He, Fan Deng   +4 more
doaj   +1 more source

Axially capacity of the CFT columns

, 2015
U radu je analizirana aksijalna nosivost CFT stubova prema sledećim standardima i kodovima: EC 4, ACI, AS, AISC, AIJ, DL/T. Razmatran je uticaj utezanja betona čeličnom cevi, odnosa d/t i e/d, skupljanja i tečenja betona, lokalnog izvijanja,veze čelične cevi i betonskog jezgra na nosivost spregnutog preseka. Prikazani su dijagrami veze napon-dilatacija
Lazović Radovanović, Marija, Deretić-Stojanović, Biljana   +1 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Instrumentation and Axial Load Testing of Displacement Piles [PDF]

, 2013
Despite the fact that results of many instrumented pile load tests have been reported in the literature, it is difficult to find well-documented instrumentation procedures that can be used when planning a load testing programme.
Salgado, Rodrigo, Prezzi, Monica, Seo, Hoyoung, Kim, Daehyeon, Bica, Adriano V.D.   +4 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source