Results 81 to 90 of about 2,898,126 (296)

Interpretable Machine Learning Algorithms to Predict the Axial Capacity of FRP-Reinforced Concrete Columns. [PDF]

Materials (Basel), 2022
Cakiroglu C, Islam K, Bekdaş G, Kim S, Geem ZW.   +4 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Research on Effect of Axial Compression Ratio on Corrugated Steel Plate-concrete Composite Shear Wall

工程科学与技术, 2020
In order to study the influence of axial compression ratio on corrugated steel plate-concrete composite shear walls(SPCSW), ABAQUS finite element software with different axial compression ratio was used for the nonlinear analysis of vertical corrugated ...
Wei WANG, Yujian LIANG, Zhaoxing XIANG, Jun WANG   +3 more
doaj  

Predicting the Ultimate Axial Capacity of Uniaxially Loaded CFST Columns Using Multiphysics Artificial Intelligence. [PDF]

Materials (Basel), 2021
Khan S, Ali Khan M, Zafar A, Javed MF, Javed MF, Aslam F, Musarat MA, Vatin NI.   +7 more
europepmc   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Optimizing performance variables for small unmanned aerial vehicle co-axial rotor systems [PDF]

, 2011
The aim of this project was to design and build a test-rig that is capable of analyzing small unmanned aerial vehicles (SUAV) co-axial rotor systems.
Stephen Prior, Brazinskas, Mantas, Prior, Stephen D., Bell, Jonathon, Mantas Brazinskas, Jonathon Bell   +5 more
core   +1 more source

RESEARCH ON THE AXIAL CARRYING CAPACITY OF ANGULAR CONTACT BALL BEARINGS BASED ON COMBINED LOADS

Jixie qiangdu, 2015
Aim at difficulty to calculate the angular contact ball bearings’ axial carrying capacity in combined loads,considering the different of every roller suffered load and the actual contact angle,using deformation coordination principle and Hertz contact ...
YAN Cheng, ZHANG YueChun, WANG Wen, LI Min, ZHANG Yong   +4 more
doaj  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Effects of Variation of Axial Load on Seismic Performance of Shear Deficient RC Exterior BCJs

International Journal of Concrete Structures and Materials, 2018
The focus of this paper is to investigate the effect of column axial load levels on the performance of shear deficient reinforced concrete beam column joints (BCJs) under monotonic and cyclic loading.
Mohammed Ali Al-Osta, Umais Khan, Mohammed Hussain Baluch, Muhammad Kalimur Rahman   +3 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source