Results 71 to 80 of about 694,679 (300)
BMC OphthalmologyBackground To assess the age and timeline distribution of ocular axial length shortening among myopic children treated with photobiomodulation therapy in the real world situations.
Kaikai Qiu +5 more
doaj +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
Features of processing exact bores of cylindrical spiral spring hone [PDF]
, 2013 Рассмотрен процесс исправления геометрических отклонений в продольном сечении с помощью варьирования интенсивности снятия слоя припуска при изменении частоты осевой осцилляции на единицу длины обрабатываемого отверстия.
Podgaetskiy, М. +5 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Supersonic axial-force characteristics of a rectangular-box cavity with various length-to-depth ratios in a flat plate [PDF]
A wind-tunnel investigation has been conducted at Mach numbers of 1.50, 2.16, and 2.86 to obtain axial-force data on a metric rectangular-box cavity with various length-to-depth ratios. The model was tested at angles of attack from -4 deg to -2 deg.
Blair, A. B., Jr., Stallings, R. L., Jr.
core +1 more source
Influence of choked angle of bearing channel on profile grain structure during multi-hole extrusion of aluminum alloy [PDF]
, 2018 Direct extrusion of aluminum alloy EN AW-6060 was carried out applying a four-hole die with pair-wise parallel and choked long channels. Due to the dissimilar friction inside parallel and choked channels profiles with different length were extruded ...
Müller, Sören, Sanabria, Vidal
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Internal fibre length concentration in a pressure screen [PDF]
, 2007 Localised axial consistency profiles within a pressure screen of a Pinus Radiata kraft pulp are reported. Axial Samples were also analysed using a Kajaani FS-200 to obtain fibre length distribution data.
Atkins, Martin John +2 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Relationship Between Macular Ganglion Cell Thickness and Ocular Elongation as Measured by Axial Length and Retinal Artery Position [PDF]
, 2020 Takashi Omoto +14 more
openalex +1 more source