Results 101 to 110 of about 257,175 (322)
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Combined mechanical loading of composite tubes [PDF]
An analytical/experimental investigation was performed to study the effect of material nonlinearities on the response of composite tubes subjected to combined axial and torsional loading.
Bowles, David E. +2 more
core +1 more source
Thick Walled Multiple Opening Reinforced Concrete Conduits [PDF]
, 1972 The Department of The Army Corps of Engineers, Engineering Division, Civil Works, Contract No.
Gamble, W.L. +3 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Investigation of creep behaviours of gypsum specimens with flaws under different uniaxial loads
Journal of Rock Mechanics and Geotechnical Engineering, 2018 The aim of this study is to identify the influence of the dip angle of a pre-existing macrocrack on the lifetime and ultimate deformation of rock-like material.
Tina Marolt Čebašek, Thomas Frühwirt
doaj +1 more source
On shakedown, ratchet and limit analysis of defective pipeline [PDF]
, 2012 In this study, the limit load, shakedown and ratchet limit of a defective pipeline subjected to constant internal pressure and a cyclic thermal gradient are analyzed.
Chen +17 more
core +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
On the numerical modelling of bond for the failure analysis of reinforced concrete [PDF]
, 2017 The structural performance of reinforced concrete relies heavily on the bond between reinforcement and concrete. In nonlinear finite element analyses, bond is either modelled by merged, also called perfect bond, or coincident with slip, also called bond ...
Grassl, Peter +2 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Structural Behaviour of Putra Block Under Axial Load Using FEM
IEM Journal, 2018 Interlocking hollow block (IHB) system is a new building technology which eliminates the mortar layer and instead provides a key connection (protrusions and grooves) to interconnect the blocks.
Pang Wei Ken +5 more
doaj +1 more source