Results 91 to 100 of about 13,446 (222)

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

open access: yesCell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du   +7 more
wiley   +1 more source

The role of neutrophils in the pathophysiology of inflammatory bowel diseases

open access: yesPeriodontology 2000, EarlyView.
Abstract Objectives Inflammatory bowel disease (IBD) encompasses a spectrum of chronic disorders of the gastrointestinal tract, with a potential bidirectional relationship with periodontitis. Neutrophils are key regulators of immune‐inflammatory responses and play a major role in both diseases.
Joao Paulo Steffens   +8 more
wiley   +1 more source

Sacroiliac and spine imaging in spondyloarthritis: Does phenotype or sex matter?

open access: yesAdvances in Rheumatology
Background Spondyloarthritis (SpA) encompasses a spectrum of immune-mediated inflammatory conditions primarily affecting the axial skeleton, including sacroiliitis and spondylitis, each with distinct features.
Gabriel Caetano Pereira   +5 more
doaj   +1 more source

Toxoplasmosis Beyond Transplantation: Diagnostic and Prevention Challenges in a Patient Receiving Targeted Immunomodulators

open access: yesTransplant Infectious Disease, EarlyView.
ABSTRACT Toxoplasmosis has long been recognized as a serious complication in immunocompromised host, particularly those with advanced HIV/AIDS, hematopoietic stem‐cell transplantation (HSCT), solid‐organ transplant (SOT), and hematological malignancies. The rapid expansion of targeted immunomodulators, including chimeric antigen receptor T‐cell (CAR‐T)
Joy Mouanes‐Abelin   +6 more
wiley   +1 more source

Sleep in ankylosing spondylitis and non-radiographic axial spondyloarthritis: associations with disease activity, gender and mood [PDF]

open access: yes, 2018
Introduction:- The study aims were to assess the prevalence of good or poor sleep in a cohort of axial spondyloarthritis patients and to investigate its correlation with a range of objectively and subjectively measured variables in order to develop a ...
Clarke, E   +7 more
core   +1 more source

Metabolic Regulation of Macrophages in Health and Disease

open access: yesMedComm, Volume 7, Issue 8, August 2026.
Extracellular metabolites drive metabolic rewiring of glucose, lipid, and amino acid pathways in macrophages, steering their polarization toward pro‐ or anti‐inflammatory phenotypes and shaping a wide range of disease processes. Macrophages from different tissues display distinct metabolic signatures, and therapeutic strategies that target these ...
Shan Huang   +6 more
wiley   +1 more source

TERAPI LATIHAN PADA ANKYLOSING SPONDYLITIS [PDF]

open access: yes, 2016
Ankylosing spondylitis adalah penyakit immune-inflamatory kronik yang mempengaruhi axial skeleton dan suatu waktu bisa mengenai sendi perifer. Perubahan patologi terjadi pada synovial, sendi tulang rawan, tendon dan ligament.
Birgita Dita Priyantono, NIM011310213011
core  

Illness Experiences of Young Women With Rheumatoid Arthritis in South Korea

open access: yesHealth Expectations, Volume 29, Issue 4, August 2026.
ABSTRACT Background Rheumatoid arthritis affects young women during critical life‐course stages, requiring ongoing adaptation to illness‐related uncertainty while managing social roles and expectations. Women in their 20s to 40s face distinctive challenges related to illness disclosure, stigma and life‐course tasks, particularly around childbirth and ...
Wonhee Baek, Hyunjung Doo
wiley   +1 more source

Microscopic gut inflammation in axial spondyloarthritis: a multiparametric predictive model [PDF]

open access: yes, 2013
Objective : To assess the rates and explore predictors of microscopic gut inflammation in a cohort of patients with axial and peripheral spondyloarthritis (SpA).
Jacques, Peggy   +11 more
core   +1 more source

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