Results 111 to 120 of about 429,043 (216)

Janus Kinase Inhibitor Use Among People With Inflammatory Disease in Australia

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Aim To describe Australian trends in JAKi uptake, where there are no restrictions on the sequence of their use in clinical practice. Methods We included all people aged 18 years and over initiating a JAKi between 1 October 2015 and 31 August 2022.
Claire T. Deakin, Michael O. Falster, Geoffrey O. Littlejohn, Peter Youssef, David Liew, Nicole L. Pratt, Sallie‐Anne Pearson   +6 more
wiley   +1 more source

Similarities and differences: disentangling the intersection between axial psoriatic arthritis and axial spondyloarthritis

Therapeutic Advances in Musculoskeletal Disease
Spondyloarthritis is a group of chronic inflammatory diseases that includes axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA). AxSpA primarily affects the axial skeleton, manifesting with hallmark features such as inflammatory back pain and a
Murat Torgutalp, Henriette Käding, Fabian Proft   +2 more
doaj   +1 more source

Defining early axial spondyloarthritis: insights and applications of the Assessment of Spondyloarthritis International Society international consensus

Journal of Rheumatic Diseases
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease with variable clinical presentation and often delayed diagnosis. The Assessment of Spondyloarthritis International Society (ASAS) recently proposed a consensus definition of early axSpA to
Tae-Jong Kim, Sofia Ramiro
doaj   +1 more source

Selection Bias in Hybrid Randomized Controlled Trials Using External Controls: A Simulation Study

Statistics in Medicine, Volume 45, Issue 25-27, November 2026.
ABSTRACT Hybrid randomized controlled trials (hybrid RCTs) integrate external control data, such as historical or concurrent data, with data from randomized trials. While numerous frequentist and Bayesian methods, such as the test‐then‐pool and the meta‐analytic‐predictive prior, have been developed to account for potential disagreement between the ...
Han Chang Chiam, Franz König, Martin Posch   +2 more
wiley   +1 more source

A Case of a Non-Radiographic Axial Spondyloarthritis in a 14-Year-Old Girl Presenting with Muscle Weakness and Hyperthyroidism

International Medical Case Reports Journal, 2020
Abdullah Elhosiny,1 Renad Alshoubaki,1 Lama Sindi,2 Sadeem Bukhari,2 Hani Almoallim1,2 1Department of Medicine, Dr. Soliman Fakeeh Hospital, Jeddah, Saudi Arabia; 2Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi ...
Elhosiny A, Alshoubaki R, Sindi L, Bukhari S, Almoallim H   +4 more
doaj  

Safety and pharmacokinetics of anumigilimab for hidradenitis suppurativa or palmoplantar pustulosis: A phase 1b study

Journal of the European Academy of Dermatology and Venereology, Volume 40, Issue 11, Page 1819-1830, November 2026.
Anumigilimab, a novel anti‐G‐CSF receptor antibody, was investigated in a phase 1b trial involving 39 patients with hidradenitis suppurativa or palmoplantar pustulosis. No serious safety concerns related to anumigilimab were noted, and PK and PD were dose dependent.
Johannes S. Kern, Simon Francis Thomsen, Georgios Kokolakis, Maurizio Podda, Gregor B. E. Jemec, Kurt Gebauer, Claus Zachariae, John Frew, Pablo Fernandez‐Peñas, Falk G. Bechara, Stefan Beissert, Sourabh Malandkar, Karen Scalzo‐Inguanti, Partha Nandy, Selvakumar Sukumar   +14 more
wiley   +1 more source

The genetics of ankylosing spondylitis and axial spondyloarthritis

, 2012
Ankylosing spondylitis (AS) and spondyloarthritis are strongly genetically determined. The long-standing association with HLA-B27 is well described, although the mechanism by which that association induces AS remains uncertain.
Robinson, P. C., Brown, Matthew A., Robinson, Philip C., Brown, Matthew A   +3 more
core   +1 more source

Epidemiology of axial spondyloarthritis

, 2016
Axial spondyloarthritis (axSpA) is an inflammatory arthritis of the sacroiliac joints and spine. The prototype is ankylosing spondylitis, the radiographic form of the disease; however, more recently, an earlier or less-differentiated presentation has ...
Liron Caplan, Michael Weisman, Lianne Gensler   +2 more
core   +1 more source

Difficult-to-Manage Axial Spondyloarthritis

Mediterranean Journal of Rheumatology
Axial spondyloarthritis (axSpA) is a multifaceted disease with a wide range of manifestations and associated comorbidities. Despite an expanding arsenal of disease-modifying anti-rheumatic drugs (DMARDs) in the treatment landscape of axSpA, a substantial number of patients remains resistant to multiple therapeutic interventions, posing a clinical ...
Emmanouilidou, Evgenia, Flouri, Irini D., Bertsias, Antonios, Kalogiannaki, Eleni, Bertsias, George, Sidiropoulos, Prodromos   +5 more
openaire   +2 more sources

Clinical characteristics, disease activity and psychosocial burden of axial spondyloarthritis in Jordan: a multicenter cross-sectional study

Scientific Reports
Axial spondyloarthritis (AxSpA) is a chronic inflammatory condition of the spine and sacroiliac joints, associated with a considerable functional and psychosocial burden.
Fatima Alnaimat, Omar Hamdan, Moayad Shaf’ei, Zaid Al-Ghazawi, Ayman AbuHelal, Ahmad Odeh, Khaldoon M Alawneh   +6 more
doaj   +1 more source