Results 91 to 100 of about 1,034,274 (259)

Unmet Needs in Spondyloarthritis: Imaging in Axial Spondyloarthritis

The Journal of Rheumatology
Imaging biomarkers in axial spondyloarthritis (axSpA) are currently the most specific biomarkers for the diagnosis of this condition. Despite advances in imaging, from plain radiographs—which detect only damage—to magnetic resonance imaging (MRI)—which identifies disease activity and structural change—there are still many challenges that remain ...
Lianne S. Gensler, Lennart Jans, Sharmila Majumdar, Denis Poddubnyy   +3 more
openaire   +2 more sources

T cells, the Next Big Target in Axial Spondyloarthritis?

Arthritis &Rheumatology, EarlyView.
Axial spondyloarthritis (axSpA) is a chronic inflammatory disease characterized by complex immune dysregulation, with T cells playing a central role in its pathogenesis. In this review, we synthesize current knowledge on diverse T cell subsets in axSpA, their pathogenic mechanisms, and emerging therapeutic strategies targeting these cells. We highlight
Mansi K. Aparnathi, Nigil Haroon
wiley   +1 more source

Advices for diagnostics of ankylosing spondylitis / axial spondyloarthritis: A review Part 2. Spinal column involvement

Consilium Medicum
This article, written by a rheumatologist and a radiologist who have been diagnosing ankylosing spondylitis – AS (axial spondyloarthritis) for many years, provides advice on the rational recognition of these diseases.
Nikolay V. Bunchuk, Antonina V. Levshakova   +1 more
doaj   +1 more source

Deep Immunophenotyping Reveals Distinct Immune Signatures in Axial Spondyloarthritis and Psoriatic Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) are overlapping yet distinct conditions within the SpA spectrum. As divergent immunophenotypes may influence disease course and therapeutic response, we compared immune cell subsets, cytokine profiles, and inflammatory mediators.
Natalie Frede, Nils Craig‐Müller, Silke Kohrt, Marei‐Theresa Bott, Ulrich Salzer, Ana Cecilia Venhoff, Jens Thiel, Julia Frede, Reinhard E. Voll, Marta Rizzi, Raquel Lorenzetti, Nils Venhoff   +11 more
wiley   +1 more source

A tale about an unusual cause of pygalgia in non‐radiographic axial spondyloarthritis

Clinical Case Reports, 2023
Schwannoma are tumors of Schwann cells of the peripheral nerve sheath. Sacral location is rarely reported especially in spondyloarthritis patients. Herein, we report a case of uncommon pygalgia in a 25‐year‐old man with history of a non‐radiographic ...
Rim Dhahri, Hiba Bettaieb, Maroua Slouma, Yasmine Khrifech, Youssef Mallat, Khalil Amri, Ahmed Harbaoui, Leila Metoui, Imen Gharsallah, Bassem Louzir   +9 more
doaj   +1 more source

Epidemiology of axial spondyloarthritis: an update [PDF]

Current Opinion in Rheumatology, 2018
Purpose of review To provide an update of the prevalence and incidence of axial spondyloarthritis in the general population and in patients with spondyloarthritis-related conditions, environmental risk factors for ankylosing spondylitis, progression from nonradiographic axial spondyloarthritis to ankylosing spondylitis ...
Runsheng, Wang, Michael M, Ward
openaire   +2 more sources

Gender differences in psychological features and determinates of quality of life in axial spondyloarthritis and psoriatic arthritis: a cross-sectional study

BMC Psychology
Background Investigating gender-specific differences in rheumatology is crucial for improving personalized treatment. The present study aimed to explore gender differences in psychological characteristics and features associated with impaired physical ...
Branko Ristic, Antonio Carletto, Elena Fracassi, Doriana Cristofalo, Maurizio Rossini, Lucia Maggioni, Giorgia Scagliosi, Olta Veliaj, Chiara Bonetto, Sarah Tosato   +9 more
doaj   +1 more source

Diffusion-weighted imaging versus short tau inversion recovery sequence: Usefulness in detection of active sacroiliitis and early diagnosis of axial spondyloarthritis. [PDF]

PLoS ONE, 2018
OBJECTIVE:To compare the utility of Diffusion weighted imaging (DWI) with short tau inversion recovery (STIR) sequence in the diagnosis of early axial spondyloarthritis (SpA).
Chiu Wai Shirley Chan, Helen Hoi Lun Tsang, Philip Hei Li, Kam Ho Lee, Chak Sing Lau, Pui Yan Stella Wong, Ho Yin Chung   +6 more
doaj   +1 more source

International Map of Axial Spondyloarthritis (IMAS): results from the perspective of 5557 patients from 27 countries around the globe

RMD Open
Background The International Map of Axial Spondyloarthritis (IMAS) is a global initiative aimed to assess the impact and burden of axial spondyloarthritis (axSpA) and identify the unmet needs from the patient’s perspective. Method IMAS is a collaboration
M. Garrido-Cumbrera, D. Poddubnyy, F. Sommerfleck, C. Bundy, S. Makri, J. Correa-Fernández, S. Akerkar, J. Lowe, E. Karam, L. Christen, V. Navarro-Compán   +10 more
semanticscholar   +1 more source

Pharmacokinetics, Effectiveness and Safety of Certolizumab Pegol in Children and Adolescents With Active Juvenile Idiopathic Arthritis: 9+‐Year Results From a Multicenter, Open‐Label Study

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients aged 2 to 17 years with ...
Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Laura Shaughnessy, Saori Shimizu, Paulette Williams, Rocío Lledó‐García, Gauri Utturkar, Baran Ufuktepe, Alberto Martini, Daniel J. Lovell, Nicolino Ruperto, the Paediatric Rheumatology International Trials Organisation (PRINTO); the Pediatric Rheumatology Collaborative Study Group (PRCSG), Hermine I. Brunner, Lyudmila Grebenkina, Irina Nikishina, Ekaterina Alexeeva, Vyacheslav Chasnyk, Carlos Abud‐Mendoza, Nadina Rubio‐Pérez, Heinrike Schmeling, María del Rocio Maldonado‐Velázquez, Diane Brown, Andrew Zeft, Esi Morgan, C. Egla Rabinovich, Daniel Kingsbury, Hulya Bukulmez, Beth Gottlieb, Thomas Griffin, Lisa Imundo, Stacey Tarvin, Earl Silverman, Alberto Martini, Daniel L. Lovell, Nicolino Ruperto   +52 more
wiley   +1 more source