Results 81 to 90 of about 15,923 (217)

Asian Pacific Association of Gastroenterology (APAGE) Clinical Practice Guidelines on the Use of Small Molecules and IL‐23 p19 Inhibitors in Ulcerative Colitis and Crohn's Disease

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Ulcerative colitis (UC) and Crohn's disease (CD) are increasingly prevalent in the Asia Pacific region, necessitating updated, region‐specific guidance on advanced therapies. Targeted small molecule agents, such as filgotinib, tofacitinib, upadacitinib, etrasimod, and ozanimod; and the IL‐23 p19 inhibitors (guselkumab, mirikizumab ...
Choon Jin Ooi, Khoon Lin Ling, Julajak Limsrivilai, Shu‐Chen Wei, Joyce Wing Yan Mak, Taku Kobayashi, Luan Minh Dang, Rupert W. Leong, Huiyu Lin, Meng‐Tzu Weng, Wan Chee Ong, Vineet Ahuja, Satimai Aniwan, Ryota Hokari, Wei Jie Jonathan Lee, Alex Hwong‐Ruey Leow, Wai‐Keung Leung, Wee‐Chian Lim, Govind Makharia, Katsuyoshi Matsuoka, Nazri Mustaffa, Siew‐Chien Ng, Mathew Philip, Pises Pisespongsa, Raja Affendi Raja Ali, Zhi Hua Ran, Marcellus Simadibrata, Jose Sollano, Malcolm Tan, Hang Dao Viet, Nik Razima Wan Ibrahim, Kai Chun Wu, Byong Duk Ye, Ida Hilmi, Asian Pacific Association of Gastroenterology (APAGE) Inflammatory Bowel Disease Committee and Asian Education Network in IBD (AEN‐IBD)   +34 more
wiley   +1 more source

Results of a non-interventional multicenter study of management of patients with non-radiological axial spondyloarthritis in real-life clinical practice in the Russian Federation (NiSpAR)

Современная ревматология
NiSpAR is a non-interventional, multicenter study whose aim was to describe a cohort of patients with non-radiological axial spondyloarthritis (nr-axSpA) and approaches to its diagnosis in the Russian Federation.Material and methods.
T. V. Dubinina, A. M. Lila, E. V. Kvasova, E. M. Agafonova, I. A. Andrianova, L. V. Ivanova, D. V. Yurk, N.  A. Garaeva, E. Y. Akulinushkina, A. N. Vedekhina, I. B. Bashkova, S. A. Lapshina, Y. Y. Grabovetskaya, N. F. Semenova, M. I. Valkova, D. G. Krechikova, O. S. Mazhaeva, I. B. Vinogradova, O. V. Bugrova, S. M. Voloshenko, G. R. Enikeeva, E. S. Immis, L. F. Timasheva, E. E. Biserova, L. Z. Shaimukhametova, I. M. Patrikeeva, A. A. Barakat, P. A. Shesternya, N. M. Nikitina, M. I. Yupatova, O. N. Anoshenkova, M. A. Korolev, Y. B. Ubshaeva, E. A. Vasilenko, E. V. Zonova, O. B. Nesmeyanova, E. A. Bogdanova, V. I. Mazurov, R. R. Samigullina, I. M. Marusenko   +39 more
doaj   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Novel Therapeutic Targets in Axial Spondyloarthritis

, 2018
Purpose of review Axial spondyloarthritis remains an area of significant unmet clinical need with only two immune pathways currently targeted by licenced therapies compared to other immune-mediated inflammatory joint disorders such as rheumatoid ...
Bowness, Paul, Worth, C, M. Hussein Al-Mossawi, Al-Mossawi, Mohammad, Claudia Worth, Bowness, P, Paul Bowness, Al-Mossawi, MH   +7 more
core   +1 more source

Impact of axial spondyloarthritis on mental health in Europe: results from the EMAS study

RMD Open, 2021
Marco Garrido-Cumbrera, Laura Christen, Souzi Makri, Christine Bundy, David Gálvez-Ruiz, Carlos J Delgado-Domínguez, Raj Mahapatra   +6 more
doaj   +1 more source

Clinical characteristics, disease activity and psychosocial burden of axial spondyloarthritis in Jordan: a multicenter cross-sectional study

Scientific Reports
Axial spondyloarthritis (AxSpA) is a chronic inflammatory condition of the spine and sacroiliac joints, associated with a considerable functional and psychosocial burden.
Fatima Alnaimat, Omar Hamdan, Moayad Shaf’ei, Zaid Al-Ghazawi, Ayman AbuHelal, Ahmad Odeh, Khaldoon M Alawneh   +6 more
doaj   +1 more source

Investigating the Effect of Tumour Necrosis Factor Antagonist on Olfaction

Clinical Otolaryngology, Volume 51, Issue 4, Page 504-511, July 2026.
ABSTRACT Objectives Tumour Necrosis factor antagonists is a potent anti‐inflammatory medication and has shown to improve olfactory function in murine models. The primary aim was to determine the effect of TNF antagonists on olfactory performance in humans.
Andreas Espehana, George Macfarlane, Elizabeth Mairenn Garden, Liam Lee, Gabija Klyvyte, Lavandan Jegatheeswaran, Rebecca Davies, Carl Philpott   +7 more
wiley   +1 more source

Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley   +1 more source

Baseline characteristics of 56 patients with non-radiographic axial spondyloarthritis.

, 2023
Baseline characteristics of 56 patients with non-radiographic axial spondyloarthritis.
Yong-Gil Kim (2622202), Oh Chan Kwon (5472983), Min-Chan Park (6723233)   +2 more
core   +1 more source

Clinical Images: Bone Buds as Precursors to Ankylosis in Axial Spondyloarthritis

Arthritis &Rheumatology, EarlyView.
Lilach Shkolnik Arad, Gleb Slobodin
wiley   +1 more source