Results 61 to 70 of about 22,657 (185)

Gender differences in psychological features and determinates of quality of life in axial spondyloarthritis and psoriatic arthritis: a cross-sectional study

BMC Psychology
Background Investigating gender-specific differences in rheumatology is crucial for improving personalized treatment. The present study aimed to explore gender differences in psychological characteristics and features associated with impaired physical ...
Branko Ristic, Antonio Carletto, Elena Fracassi, Doriana Cristofalo, Maurizio Rossini, Lucia Maggioni, Giorgia Scagliosi, Olta Veliaj, Chiara Bonetto, Sarah Tosato   +9 more
doaj   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, Accepted Article.
Objectives The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in non‐lymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

Efficacy and Safety of Ixekizumab in the Treatment of Radiographic Axial Spondyloarthritis:Sixteen-Week Results From a Phase III Randomized, Double-Blind, Placebo-Controlled Trial in Patients With Prior Inadequate Response to or Intolerance of Tumor Necrosis Factor Inhibitors [PDF]

, 2019
Objective: To investigate the efficacy and safety of ixekizumab in patients with active radiographic axial spondyloarthritis (SpA) and prior inadequate response to or intolerance of 1 or 2 tumor necrosis factor inhibitors (TNFi).
Antolini, Christopher, Azevedo, Valderilio, Barkham, Magnus, Barragan, Sergio Duran, Berman, Alberto, Blasco, Francisco Navarro, Blicharski, Tomasz, Brzezicki, Jan, Burmester, Gerd, Carlier, Hilde, Carrio, Judith, Cocco, Jose Maldonado, Collantes, Eduardo, Combe, Bernard, Cons‐Molina, Fidencio, Cortes‐Maisonet, Gregorio, Deodhar, Atul, Dudek, Anna, Elkayam, Ori, Fernandez, Carlos Gonzalez, Flint, Kathleen, Gaffney, Karl, Galeazzi, Mauro, Gaylis, Norman, Goddard, David, Goupille, Philippe, Greenwald, Maria, Gremese, Elisa, Hong, Seung Jae, Howell, Mary, Hrycaj, Pawel, Ince, Akgun, Jesus, Amarilis Perez‐De, Ju, Ji Hyeon, Järvinen, Pentti, Kaine, Jeffrey, Kang, Seong Wook, Keiserman, Mauro, Kim, Tae‐Hwan, Kivitz, Alan, Klein, Steven, Kremer, Joel, Krishnan, Eswar, Lee, Chang Keun, Lee, Eun Bong, Lee, Sang Heon, Lee, Sang‐Hoon, Lespessailles, Eric, Li, Xiaoqi, Lidman, Roger, Loveless, James, Lucero, Eleonora, Marcolino, Flora, Mariette, Xavier, Masmitja, Jordi Gratacos, Mehta, Daksha, Morin, Frederic, Moscovici, Yolanda, Mueller, Eric, Mysler, Eduardo, Nguyen, Minh,, Pacheco‐Tena, Cesar, Pantojas, Carlos, Park, Min‐Chan, Peters, Eric, Plebanski, Rafal, Poddubnyy, Denis, Querubin, Roel, Rahman, Proton, Reitblat, Tatiana, Remus, Cesar Ramos, Reveille, John, Rivera, Tania, Rodriguez, Aaron Alejandro Barrera, Rodriguez, Juan Cruz Rizo, Salvarani, Carlo, Sanchez‐Burson, Juan, Sande, Marleen, Santisteban, Silvia, Sayers, Michael, Scotton, Antonio, Scoville, Craig, Shaw, David, Shin, Kichul, Singhal, Atul, Skinner, Cassandra, Soto‐Raices, Oscar, Soubrier, Martin, Szymanska, Malgorzata, Thai, Christine, Wells, Alvin, Wojciechowski, Rafal, Xavier, Ricardo,, Ximenes, Antonio, Zhao, Fangyi, Zisman, Devy   +95 more
core   +6 more sources

Facilitating Expedited Drug Approval—the Past, Present, and Future of Clinical Trials for Pediatric Rheumatic Disease

Arthritis Care &Research, EarlyView.
Pamela F. Weiss, Hermine I. Brunner
wiley   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis within a Longitudinal Cohort

Arthritis &Rheumatology, Accepted Article.
Objective To estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axSpA and to identify factors associated with D2M/TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis Program cohort.
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

Long non-coding RNA (H19) in patients with spondyloarthritis: association with disease parameters and ultrasonographic findings

Egyptian Rheumatology and Rehabilitation
Background Spondyloarthritis is a well-known chronic inflammatory disorder; despite recent advances, its genetic basis remains poorly understood. Recently, long non-coding RNA (H19) was identified to be associated with various human cancers and studied ...
A. I. EL-Zwawy, Eiman Soliman, Eman T. Elsayed, Mai M. Morsy   +3 more
doaj   +1 more source

Recommendations for the treatment of axial spondyloarthritis: An analysis of the updated ASAS/EULAR 2022 clinical guidelines

Научно-практическая ревматология
The article discusses the 2022 updated version of the collaborative ASAS/EULAR (Assessment in SpondyloArthritis international Society/European Alliance of Associations for Rheumatology) recommendations for the treatment of axial spondyloarthritis.
Sh. F. Erdes, T. V. Dubinina
doaj   +1 more source

Diagnostic accuracy of inflammatory back pain for axial spondyloarthritis in rheumatological care [PDF]

, 2018
Objective: Inflammatory back pain (IBP), the key symptom of axial spondyloarthritis (axSpA), including ankylosing spondylitis, has been proposed as a screening test for patients presenting with chronic back pain in primary care.
Braun, Juergen, Callhoff, Johanna, Listing, Joachim, Poddubnyy, Denis, Rudwaleit, Martin, Sieber, Joachim, Spiller, Inge   +6 more
core   +1 more source

Monocytes with trained immunity–like signatures are associated with acute anterior uveitis in ankylosing spondylitis

Interdisciplinary Medicine, EarlyView.
In ankylosing spondylitis‐acute anterior uveitis (AS‐AAU), trained immunity monocytes (Mono‐TI) differentiate into macrophages in the eye, retaining trained immunity features. Mono‐TI cells secrete pro‐inflammatory cytokines and chemokines, including IL‐1β, TNF‐α, and CCL3.
Yimeng Sun, Lu Zhang, Xinyu Yao, Yunfei Liu, Xin Li, Feng Wen, Yong Dai, Ye Dai, Ziyu Du, Dijie Qiao, Ziwei Meng, Cong Hu, Chun Yan, Wei Chi   +13 more
wiley   +1 more source

Successful treatment of eosinophilic esophagitis with upadacitinib prescribed for atopic dermatitis

JPGN Reports, EarlyView.
Abstract We describe a pediatric patient treated with upadacitinib for atopic dermatitis (AD) who subsequently achieved sustained clinical and histologic remission of eosinophilic esophagitis (EoE). Upadacitinib is an oral small molecule selective Janus kinase 1 inhibitor that inhibits janus kinase‐signal transduction and activation of transcription ...
Nathalie Nguyen, Maureen Bauer
wiley   +1 more source