Results 121 to 130 of about 304,829 (369)

Sustained Release of Proteins Using Region‐Specific Tunable Degradability in Hydrogels through 3D Photopatterning and Complimentary Labile Bond Chemistry

open access: yesAdvanced Functional Materials, EarlyView.
A series of ultraviolet‐ and near‐infrared radiation sensitive photoactivatable hydrogels are developed that can be controlled spatiotemporally down to µm precisions using one‐ and two‐photon uncaging. The latent hydroxylamine‐, hydrazine‐, and amine uncaged moieties are used to photopattern a series of diverse proteins displaying complimentary ...
Tove Kivijärvi   +6 more
wiley   +1 more source

dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway

open access: yesScience, 2012
Sarm-Assisted Suicide Neurodegenerative disease or nerve lesions cause axons and synapses to disintegrate through a process known as Wallerian degeneration, which may involve an active “axon death program.” Osterloh et al. (p.
Jeannette M. Osterloh   +21 more
semanticscholar   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

open access: yesAdvanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García   +23 more
wiley   +1 more source

Axcaliber: A method for measuring axon diameter distribution from diffusion MRI

open access: yesMagnetic Resonance in Medicine, 2008
The diameter of a myelinated nerve axon is directly proportional to its conduction velocity, so the axon diameter distribution helps determine the channel capacity of nervous transmission along fascicles in the central (CNS) and peripheral nervous ...
Y. Assaf   +3 more
semanticscholar   +1 more source

N-Propionylmannosamine stimulates axonal elongation in a murine model of sciatic nerve injury

open access: yesNeural Regeneration Research, 2015
Increasing evidence indicates that sialic acid plays an important role during nerve regeneration. Sialic acids can be modified in vitro as well as in vivo using metabolic oligosaccharide engineering of the N-acyl side chain.
Christian Witzel   +3 more
doaj   +1 more source

Biointerfacing with AgBiS2 Quantum Dots for Pseudocapacitive Photostimulation

open access: yesAdvanced Functional Materials, EarlyView.
It is demonstrated that AgBiS2 quantum dots exhibit unique photoinduced pseudocapacitive charge transfer properties, enabling efficient light‐to‐electrical energy conversion. These quantum dots facilitate enhanced light absorption and transduction when integrated with ZnO nanowires, which serve as an effective charge transport medium.
Ridvan Balamur   +8 more
wiley   +1 more source

A rise in NAD precursor nicotinamide mononucleotide (NMN) after injury promotes axon degeneration

open access: yesCell Death and Differentiation, 2014
NAD metabolism regulates diverse biological processes, including ageing, circadian rhythm and axon survival. Axons depend on the activity of the central enzyme in NAD biosynthesis, nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2), for their ...
M. D. Stefano   +22 more
semanticscholar   +1 more source

The effects of cyclical simulation on the axon hillock diameter of murine intracortical neurons [PDF]

open access: yesarXiv, 2018
Changes to the axon hillock in frequently firing neurons are known to be important predictors of early disease states. Studying this phenomenon is critical to understanding the first insult implicated in multiple neuro-degenerative disorders. To study these changes we used cyclical stimulations using micro-electrodes to the axon hillock of mouse ...
arxiv  

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

Differential signaling via the same axon of neocortical pyramidal neurons.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1998
The nature of information stemming from a single neuron and conveyed simultaneously to several hundred target neurons is not known. Triple and quadruple neuron recordings revealed that each synaptic connection established by neocortical pyramidal neurons
H. Markram, Yun Wang, M. Tsodyks
semanticscholar   +1 more source

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