Results 151 to 160 of about 899,641 (334)

High‐Throughput Proteoform Imaging for Revealing Spatial‐Resolved Changes in Brain Tissues Associated with Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
High‐throughput proteoform imaging (HTPi) is established by combining matrix‐assisted laser desorption ionization mass spectrometry imaging and high‐sensitivity region‐specific top‐down proteomic analysis. HTPi enables the generation of annotated proteoform images with exceptional precision, high throughput, and deep coverage, showing distinct spatial ...
Yue Sun   +8 more
wiley   +1 more source

Neuropilin-2 Is Required In Vivo for Selective Axon Guidance Responses to Secreted Semaphorins [PDF]

open access: bronze, 2000
Roman J. Giger   +12 more
openalex   +1 more source

Longitudinal, Multimodal Tracking Reveals Lasting Neurovascular Impact of Individual Microinfarcts

open access: yesAdvanced Science, EarlyView.
Jin et al. investigate the neurovascular impact of microinfarcts, revealing transient neural suppression with minimal cell death and recovery linked to vascular remodeling. Fast‐spiking interneurons exhibit reduced excitability, whereas regular‐spiking neurons showed increased bursting activity. Disruptions in low‐gamma phase locking suggest persistent
Yifu Jin   +9 more
wiley   +1 more source

Roles of Fibroblast Growth Factors in the Axon Guidance. [PDF]

open access: yesInt J Mol Sci, 2023
Zhang W   +6 more
europepmc   +1 more source

Retinal Ganglion Cell Axon Guidance in the Mouse Optic Chiasm: Expression and Function of Robos and Slits [PDF]

open access: hybrid, 2000
Lynda Erskine   +7 more
openalex   +1 more source

MAGEA6 Engages a YY1‐Dependent Transcription to Dictate Perineural Invasion in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the role of MAGEA6 in perineural invasion (PNI) in colorectal cancer (CRC). MAGEA6 promotes CRC invasiveness by inhibiting YY1 ubiquitination, enhancing CXCL1 secretion, and recruiting Schwann cells. These findings highlight the potential of targeting the MAGEA6/YY1/CXCL1 axis for therapeutic strategies against PNI and tumor ...
Hao Wang   +9 more
wiley   +1 more source

Loss of oligodendrocyte ErbB receptor signaling leads to hypomyelination, reduced density of parvalbumin‐expressing interneurons, and inhibitory function in the auditory cortex

open access: yesGlia, Volume 71, Issue 2, Page 187-204, February 2023., 2023
Main Point Loss of oligodendrocyte ErbB receptor signaling leads to A1 hypomyelination, reduced PV expression and density of PV+ neurons and synapses, hypoconnectivity of inhibitory circuits and shift of the E/I balance towards excitation. Abstract For a long time, myelin was thought to be restricted to excitatory neurons, and studies on dysmyelination
Beatriz C. Borges   +4 more
wiley   +1 more source

Axon guidance molecules

open access: yesCell, 1995
Geoffrey M.W. Cook, Roger J. Keynes
openaire   +3 more sources

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