Results 261 to 270 of about 102,974 (302)

Axon guidance and somites

Cell and Tissue Research, 1997
The segmental arrangement of spinal nerves in higher vertebrate embryos provides a simple system in which to study the factors that influence axon pathfinding. Developing motor and sensory axons are intimately associated with surrounding tissues that direct axon guidance. We argue that two distinct guidance mechanisms, viz.
, Tannahill, , Cook, , Keynes
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Longitudinal axon guidance

Current Opinion in Neurobiology, 2006
Our knowledge about molecular mechanisms underlying axon guidance along the antero-posterior axis in contrast to the dorso-ventral axis of the developing nervous system is very limited. During the past two years in vitro and in vivo studies have indicated that morphogens have a role in longitudinal axon guidance.
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Calcium signaling in axon guidance

Trends in Neurosciences, 2014
Guidance of axons to their targets in the developing nervous system requires a myriad of downstream signaling molecules to coordinate growth cone movement. One of the most important of these is calcium, and over the past few years many new insights have been gained into the role of calcium in axon guidance.
Sutherland, Daniel J., Pujic, Zac, Goodhill, Geoffrey J.   +2 more
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Axon guidance: the cytoplasmic tail

Current Opinion in Cell Biology, 2002
Recent advances in the study of axon guidance have begun to clarify the intricate signalling mechanisms utilised by receptors that mediate path-finding. Many of these axon guidance receptors, including Plexin B, EphA, ephrin B and Robo, regulate the Rho family of GTPases, to effect changes in motility. Recent studies demonstrate a critical role for the
Bharatkumar N, Patel, David L, Van Vactor   +1 more
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Diffusion in Axon Guidance

European Journal of Neuroscience, 1997
AbstractAxon guidance by target‐derived diffusible factors plays an important role in the development of the nervous system. This paper considers the constraints imposed on this process by the mathematics of diffusion. A point source continuously producing a factor into an infinite three‐dimensional volume is considered as a model for both the in vivo ...
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Repellent cues in axon guidance

Current Opinion in Neurobiology, 1992
There is increasing evidence that axons are guided by repulsion in several regions of the developing nervous system, although this has yet to be confirmed directly in vivo. As more candidate repulsion molecules are identified, it is becoming clear that collapse of the growth cone in vitro may be mediated by more than one intracellular mechanism.
R J, Keynes, G M, Cook
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Wnt signaling in axon guidance

Trends in Neurosciences, 2004
Recent studies have identified Wnt proteins as conserved axon guidance molecules in vertebrates and invertebrates. Wnt proteins are a large family of diffusible factors that play several important roles, both in embryonic development and in adult function.
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Ephrin signaling in axon guidance

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2004
The multiple functions of a neuron depend on the proper assembly of axonal connections during the development of the nervous systems. This assembly involves the motile behavior of growth cones at the ends of elongating axons. The growth cones express receptors that bind to specific guidance molecules in the local environment.
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Attractive Axon Guidance Molecules

Science, 1994
Baier, H., Bonhoeffer, F.
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ER stress transforms random olfactory receptor choice into axon targeting precision

Cell, 2022
Stavros Lomvardas
exaly