Results 151 to 160 of about 122,498 (328)

Axonal Transport Defect in Gigaxonin Deficiency Rescued by Tubastatin A. [PDF]

Neurotherapeutics, 2023
Nath B, Phaneuf D, Julien JP.
europepmc   +1 more source

Stable and metastable cytoskeletal polymers carried by slow axonal transport [PDF]

, 1988
Ghislaine Filliatreau, Philippe Denoulet, Béatrice de Néchaud, Luigi Di Giamberardino   +3 more
openalex   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Paclitaxel inhibits mRNA transport in axons

Neurobiology of Disease, 2015
Paclitaxel is an integral component of solid tumor treatment. This chemotherapeutic agent provokes an often irreversible peripheral sensory neuropathy with pathological features of distal axonal degeneration.
Ilja Bobylev, Abhijeet R. Joshi, Mohammed Barham, Christian Ritter, Wolfram F. Neiss, Ahmet Höke, Helmar C. Lehmann   +6 more
doaj  

Axonal Transport of Lysosomes Is Unaffected in Glucocerebrosidase-Inhibited iPSC-Derived Forebrain Neurons. [PDF]

eNeuro, 2023
Keefe AJ, Gabrych DR, Zhu Y, Vocadlo DJ, Silverman MA.   +4 more
europepmc   +1 more source

Metabolic and ionic requirements for the intra‐axonal transport of noradrenaline in the cat hypogastric nerve

, 1973
S. M. Kirpekar, J. C. Prat, A R Wakade
openalex   +2 more sources

Reduced anterograde and retrograde accumulation of axonally transported phosphofructokinase in streptozotocin-diabetic rats: effects of insulin and the aldose reductase inhibitor ?Statil? [PDF]

, 1987
Gary B. Willars, Nigel A. Calcutt, David R. Tomlinson   +2 more
openalex   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Coexpression of GSK-3β Corrects Phenotypic Aberrations of Dorsal Root Ganglion Cells, Cultured from Adult Transgenic Mice Overexpressing Human Protein tau

Neurobiology of Disease, 2002
Coexpression of constitutively active GSK-3β[S9A] rescued the axonal pathology induced by overexpression of human tau in transgenic mice (Spittaels et al., (2000) J. Biol. Chem. 275, 41340–41349).
R. Nuydens, G. Van Den Kieboom, C. Nolten, C. Verhulst, P. Van Osta, K. Spittaels, C. Van den Haute, E. De Feyter, H. Geerts, F. Van Leuven   +9 more
doaj  

Axonal transport deficits in the pathogenesis of diabetic peripheral neuropathy. [PDF]

Front Endocrinol (Lausanne), 2023
Yang C, Zhao X, An X, Zhang Y, Sun W, Zhang Y, Duan Y, Kang X, Sun Y, Jiang L, Lian F.   +10 more
europepmc   +1 more source