Results 151 to 160 of about 68,755 (290)

Role of LRRK2 in axonal transport and Parkinson's disease. [PDF]

Biochem J
Twellsieck B, Boecker CA.
europepmc   +1 more source

Axonal transport deficits in the pathogenesis of diabetic peripheral neuropathy. [PDF]

Front Endocrinol (Lausanne), 2023
Yang C, Zhao X, An X, Zhang Y, Sun W, Zhang Y, Duan Y, Kang X, Sun Y, Jiang L, Lian F.   +10 more
europepmc   +1 more source

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Axonal transport deficits in neuropsychiatric disorders. [PDF]

Mol Cell Neurosci, 2022
Badal KK, Puthanveettil SV.
europepmc   +1 more source

iabetic Encephalopathy Affecting Mitochondria and Axonal Transport Proteins

, 2020
Maryam Eslami
openalex   +1 more source

Phosphorylation of the Bruchpilot N-terminus in Drosophila unlocks axonal transport of active zone building blocks [PDF]

, 2019
J.H. Driller, Janine Lützkendorf, Harald Depner, Matthias Siebert, Benno Kuropka, Christoph Weise, Chengji Piao, Astrid G. Petzoldt, Martin Lehmann, Ulrich Stelzl, René P. Zahedi, Albert Sickmann, Christian Freund, Stephan J. Sigrist, M.C. Wahl   +14 more
openalex   +1 more source

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Axonal transport of Frizzled5 by Alcadein α-containing vesicles is associated with kinesin-1. [PDF]

Mol Biol Cell, 2023
Shiraki Y, Mitsuma M, Takada R, Hata S, Kitamura A, Takada S, Kinjo M, Taru H, Müller UC, Yamamoto T, Sobu Y, Suzuki T.   +11 more
europepmc   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, EarlyView.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

CDKL5 regulates the initiation of retrograde axonal transport through CLIP170-dynactin complex formation. [PDF]

FEBS J
Baldin S, Carmone C, Valetti G, De Rosa R, Barbiero I.   +4 more
europepmc   +1 more source