Results 31 to 40 of about 1,949 (177)

Ayahuasca drinking using a two-bottle choice procedure in male mice

Scientific Reports
Ayahuasca has been proposed as a treatment for substance use disorders. However, because of its hallucinogenic properties, studies investigating its abuse potential are needed.
Natali D. Kisaki, Yasmim A. Serra, Isa R. S. Rodrigues, Kallyane S. O. Silva, Caio Jovita-Farias, Gérson L. Alves, Marcus T. M. Bezerra, Isabelle Gaburro-Ribeiro, João P. C. Leite, Nailton M. S. Jesus, Alexandre J. Oliveira-Lima, Lais F. Berro, Eduardo A. V. Marinho   +12 more
doaj   +1 more source

Ayahuasca: Uses, Phytochemical and Biological Activities

Natural Products and Bioprospecting, 2019
Ayahuasca (caapi, yajé), is a psychoactive brew from the Amazon Basin region of South America traditionally considered a “master plant.” It is prepared as a decoction from Banisteriopsis caapi and Psychotria viridis, which it is thought that it ...
Edgar Antonio Estrella-Parra, Julio Cesar Almanza-Pérez, Francisco Javier Alarcón-Aguilar   +2 more
doaj   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

A quantitative textual analysis of the subjective effects of ayahuasca in naïve users with and without depression

Scientific Reports, 2023
Ayahuasca is a brew with psychoactive properties that has been used as an entheogen for centuries, with more recent studies suggesting it is a promising treatment for some clinical disorders.
Lucas Cruz, Bheatrix Bienemann, Fernanda Palhano-Fontes, Luís Fernando Tófoli, Dráulio B. Araújo, Daniel C. Mograbi   +5 more
doaj   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Evaluation of the Cytotoxicity of Ayahuasca Beverages [PDF]

Molecules, 2020
Ayahuasca is a beverage consumed at shamanic ceremonies and currently has gained popularity on recreational scenarios. It contains beta-carboline alkaloids and N,N-dimethyltryptamine, which possesses hallucinogenic effects. Only a few studies have elicited the psychoactive effects and the dose of such compounds on neurological dopaminergic cells or ...
Ana Y. Simão, Joana Gonçalves, Ana Gradillas, Antonia García, José Restolho, Nicolás Fernández, Jesus M. Rodilla, Mário Barroso, Ana Paula Duarte, Ana C. Cristóvão, Eugenia Gallardo   +10 more
openaire   +4 more sources

Effects of Long-Term Ayahuasca Administration on Memory and Anxiety in Rats. [PDF]

PLoS ONE, 2015
Ayahuasca is a hallucinogenic beverage that combines the action of the 5-HT2A/2C agonist N,N-dimethyltryptamine (DMT) from Psychotria viridis with the monoamine oxidase inhibitors (MAOIs) induced by beta-carbonyls from Banisteriopsis caapi.
Vanessa Manchim Favaro, Maurício Yonamine, Juliana Carlota Kramer Soares, Maria Gabriela Menezes Oliveira   +3 more
doaj   +1 more source

Contextualising Mental Privacy in South Africa: Legal, Ethical, and Socio‐Cultural Considerations With Policy Recommendations

Developing World Bioethics, EarlyView.
ABSTRACT Mental privacy is a growing concern as neurotechnologies and digital mental health tools collect and process sensitive brain‐related data. In South Africa, cultural and religious diversity adds complexity to protecting mental privacy, with traditional healing practices, communal decision‐making, and spiritual beliefs influencing mental health ...
Marietjie Botes, Melodie Labuschaigne, Camille Casteleyn, Becky Inkster, Mark Sheppard   +4 more
wiley   +1 more source

An ontogenic study of the behavioral effects of chronic intermittent exposure to ayahuasca in mice

Brazilian Journal of Medical and Biological Research
Ayahuasca is a beverage obtained from decoctions of the Banisteriopsis caapi plus Psychotria viridis. In religious contexts, ayahuasca is used by different age groups.
N.F. Correa-Netto, M.Y. Masukawa, F. Nishide, G.S. Galfano, F. Tamura, M.K. Shimizo, M.P. Marcato, J.G. Santos Junior, A. Linardi   +8 more
doaj   +1 more source

Music Playlist Use in Clinical Trials of Psychedelic Assisted Psychotherapy: A Systematic Review

Journal of Clinical Psychology, Volume 82, Issue 9, Page 1263-1270, September 2026.
ABSTRACT Recent studies have shown promising results for psychedelics in the treatment of psychiatric disorders. Both in clinical and recreational settings, contextual elements, such as music, can influence the experience of users and may be linked to positive outcomes.
Lucas Cruz, Fernando R. Beserra, Julia M. K. Freind, Sandro E. Rodrigues, Daniel C. Mograbi   +4 more
wiley   +1 more source